WEB-based GEne SeT AnaLysis Toolkit
	Translating gene lists into biological insights...

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User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: .05, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:

• C: the number of reference genes in the category
• O: the number of genes in the gene set and also in the category
• E: the expected number in the category
• R: ratio of enrichment
• rawP: p value from hypergeometric test
• adjP: p value adjusted by the multiple test adjustment

Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway       Name:Osteoclast differentiation       ID:04380
C=128; O=44; E=3.98; R=11.06; rawP=8.22e-34; adjP=1.50e-31
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000131042	NA	LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	10288	ENSG00000131042
2	ENSG00000095970	NA	TREM2	triggering receptor expressed on myeloid cells 2	54209	ENSG00000095970
3	ENSG00000104972	NA	LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	10859	ENSG00000104972
4	ENSG00000106799	NA	TGFBR1	transforming growth factor, beta receptor 1	7046	ENSG00000106799
5	ENSG00000107758	NA	PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	5532	ENSG00000107758
6	ENSG00000043462	NA	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	3937	ENSG00000043462
7	ENSG00000170909	NA	OSCAR	osteoclast associated, immunoglobulin-like receptor	126014	ENSG00000170909
8	ENSG00000116701	NA	NCF2	neutrophil cytosolic factor 2	4688	ENSG00000116701
9	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
10	ENSG00000150337	NA	FCGR1A	Fc fragment of IgG, high affinity Ia, receptor (CD64)	2209	ENSG00000150337
11	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
12	ENSG00000158517	NA	NCF1	neutrophil cytosolic factor 1	653361	ENSG00000158517
13	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
14	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
15	ENSG00000239998	NA	LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	11027	ENSG00000239998
16	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
17	ENSG00000066336	NA	SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	6688	ENSG00000066336
18	ENSG00000165025	NA	SYK	spleen tyrosine kinase	6850	ENSG00000165025
19	ENSG00000141655	NA	TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	8792	ENSG00000141655
20	ENSG00000165168	NA	CYBB	cytochrome b-245, beta polypeptide	1536	ENSG00000165168
21	ENSG00000072694	NA	FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	2213	ENSG00000072694
22	ENSG00000186818	NA	LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	11006	ENSG00000186818
23	ENSG00000100365	NA	NCF4	neutrophil cytosolic factor 4, 40kDa	4689	ENSG00000100365
24	ENSG00000159128	NA	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)	3460	ENSG00000159128
25	ENSG00000010671	NA	BTK	Bruton agammaglobulinemia tyrosine kinase	695	ENSG00000010671
26	ENSG00000170866	NA	LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	11026	ENSG00000170866
27	ENSG00000101307	NA	SIRPB1	signal-regulatory protein beta 1	10326	ENSG00000101307
28	ENSG00000162747	NA	FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	2215	ENSG00000162747
29	ENSG00000095585	NA	BLNK	B-cell linker	29760	ENSG00000095585
30	ENSG00000203747	NA	FCGR3A	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)	2214	ENSG00000203747
31	ENSG00000115594	NA	IL1R1	interleukin 1 receptor, type I	3554	ENSG00000115594
32	ENSG00000051523	NA	CYBA	cytochrome b-245, alpha polypeptide	1535	ENSG00000051523
33	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
34	ENSG00000184371	NA	CSF1	colony stimulating factor 1 (macrophage)	1435	ENSG00000184371
35	ENSG00000104974	NA	LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	11024	ENSG00000104974
36	ENSG00000143226	NA	FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	2212	ENSG00000143226
37	ENSG00000105609	NA	LILRB5	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5	10990	ENSG00000105609
38	ENSG00000067182	NA	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	7132	ENSG00000067182
39	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
40	ENSG00000011600	NA	TYROBP	TYRO protein tyrosine kinase binding protein	7305	ENSG00000011600
41	ENSG00000244482	NA	LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	79168	ENSG00000244482
42	ENSG00000204577	NA	LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	11025	ENSG00000204577
43	ENSG00000102575	NA	ACP5	acid phosphatase 5, tartrate resistant	54	ENSG00000102575
44	ENSG00000182578	NA	CSF1R	colony stimulating factor 1 receptor	1436	ENSG00000182578

Database:KEGG pathway       Name:Cytokine-cytokine receptor interaction       ID:04060
C=265; O=57; E=8.23; R=6.92; rawP=3.64e-31; adjP=3.33e-29
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000161955	NA	TNFSF13	tumor necrosis factor (ligand) superfamily, member 13	8741	ENSG00000161955
2	ENSG00000167236	NA	CCL23	chemokine (C-C motif) ligand 23	6368	ENSG00000167236
3	ENSG00000172724	NA	CCL19	chemokine (C-C motif) ligand 19	6363	ENSG00000172724
4	ENSG00000134470	NA	IL15RA	interleukin 15 receptor, alpha	3601	ENSG00000134470
5	ENSG00000126353	NA	CCR7	chemokine (C-C motif) receptor 7	1236	ENSG00000126353
6	ENSG00000146072	NA	TNFRSF21	tumor necrosis factor receptor superfamily, member 21	27242	ENSG00000146072
7	ENSG00000227507	NA	LTB	lymphotoxin beta (TNF superfamily, member 3)	4050	ENSG00000227507
8	ENSG00000102524	NA	TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b	10673	ENSG00000102524
9	ENSG00000106799	NA	TGFBR1	transforming growth factor, beta receptor 1	7046	ENSG00000106799
10	ENSG00000174564	NA	IL20RB	interleukin 20 receptor beta	53833	ENSG00000174564
11	ENSG00000131724	NA	IL13RA1	interleukin 13 receptor, alpha 1	3597	ENSG00000131724
12	ENSG00000150782	NA	IL18	interleukin 18 (interferon-gamma-inducing factor)	3606	ENSG00000150782
13	ENSG00000173535	NA	TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	8794	ENSG00000173535
14	ENSG00000106952	NA	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	944	ENSG00000106952
15	ENSG00000134853	NA	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	5156	ENSG00000134853
16	ENSG00000110944	NA	IL23A	interleukin 23, alpha subunit p19	51561	ENSG00000110944
17	ENSG00000119535	NA	CSF3R	colony stimulating factor 3 receptor (granulocyte)	1441	ENSG00000119535
18	ENSG00000111321	NA	LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)	4055	ENSG00000111321
19	ENSG00000100368	NA	CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	1439	ENSG00000100368
20	ENSG00000161921	NA	CXCL16	chemokine (C-X-C motif) ligand 16	58191	ENSG00000161921
21	ENSG00000163823	NA	CCR1	chemokine (C-C motif) receptor 1	1230	ENSG00000163823
22	ENSG00000134352	NA	IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	3572	ENSG00000134352
23	ENSG00000162892	NA	IL24	interleukin 24	11009	ENSG00000162892
24	ENSG00000115590	NA	IL1R2	interleukin 1 receptor, type II	7850	ENSG00000115590
25	ENSG00000177663	NA	IL17RA	interleukin 17 receptor A	23765	ENSG00000177663
26	ENSG00000150281	NA	CTF1	cardiotrophin 1	1489	ENSG00000150281
27	ENSG00000077238	NA	IL4R	interleukin 4 receptor	3566	ENSG00000077238
28	ENSG00000141655	NA	TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	8792	ENSG00000141655
29	ENSG00000113721	NA	PDGFRB	platelet-derived growth factor receptor, beta polypeptide	5159	ENSG00000113721
30	ENSG00000173578	NA	XCR1	chemokine (C motif) receptor 1	2829	ENSG00000173578
31	ENSG00000163736	NA	PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	5473	ENSG00000163736
32	ENSG00000108688	NA	CCL7	chemokine (C-C motif) ligand 7	6354	ENSG00000108688
33	ENSG00000104432	NA	IL7	interleukin 7	3574	ENSG00000104432
34	ENSG00000159128	NA	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)	3460	ENSG00000159128
35	ENSG00000175505	NA	CLCF1	cardiotrophin-like cytokine factor 1	23529	ENSG00000175505
36	ENSG00000198223	NA	CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	1438	ENSG00000198223
37	ENSG00000120889	NA	TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	8795	ENSG00000120889
38	ENSG00000180871	NA	CXCR2	chemokine (C-X-C motif) receptor 2	3579	ENSG00000180871
39	ENSG00000124875	NA	CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	6372	ENSG00000124875
40	ENSG00000121807	NA	CCR2	chemokine (C-C motif) receptor 2	729230	ENSG00000121807
41	ENSG00000096996	NA	IL12RB1	interleukin 12 receptor, beta 1	3594	ENSG00000096996
42	ENSG00000136634	NA	IL10	interleukin 10	3586	ENSG00000136634
43	ENSG00000110324	NA	IL10RA	interleukin 10 receptor, alpha	3587	ENSG00000110324
44	ENSG00000241839	NA	PLEKHO2	pleckstrin homology domain containing, family O member 2	80301	ENSG00000241839 ENSG00000249240
45	ENSG00000026103	NA	FAS	Fas (TNF receptor superfamily, member 6)	355	ENSG00000026103
46	ENSG00000115594	NA	IL1R1	interleukin 1 receptor, type I	3554	ENSG00000115594
47	ENSG00000028137	NA	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	7133	ENSG00000028137
48	ENSG00000184371	NA	CSF1	colony stimulating factor 1 (macrophage)	1435	ENSG00000184371
49	ENSG00000115607	NA	IL18RAP	interleukin 18 receptor accessory protein	8807	ENSG00000115607
50	ENSG00000067182	NA	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	7132	ENSG00000067182
51	ENSG00000145623	NA	OSMR	oncostatin M receptor	9180	ENSG00000145623
52	ENSG00000181374	NA	CCL13	chemokine (C-C motif) ligand 13	6357	ENSG00000181374
53	ENSG00000134460	NA	IL2RA	interleukin 2 receptor, alpha	3559	ENSG00000134460
54	ENSG00000125735	NA	TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	8740	ENSG00000125735
55	ENSG00000163464	NA	CXCR1	chemokine (C-X-C motif) receptor 1	3577	ENSG00000163464
56	ENSG00000006074	NA	CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	6362	ENSG00000006074
57	ENSG00000182578	NA	CSF1R	colony stimulating factor 1 receptor	1436	ENSG00000182578

Database:KEGG pathway       Name:Staphylococcus aureus infection       ID:05150
C=55; O=26; E=1.71; R=15.21; rawP=7.50e-25; adjP=4.58e-23
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000224389	NA	C4B	complement component 4B (Chido blood group)	721	ENSG00000224389
2	ENSG00000125730	NA	C3	complement component 3	718	ENSG00000125730
3	ENSG00000169403	NA	PTAFR	platelet-activating factor receptor	5724	ENSG00000169403
4	ENSG00000072694	NA	FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	2213	ENSG00000072694
5	ENSG00000110876	NA	SELPLG	selectin P ligand	6404	ENSG00000110876
6	ENSG00000244731	NA	C4A	complement component 4A (Rodgers blood group)	720	ENSG00000244731
7	ENSG00000169896	NA	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	3684	ENSG00000169896
8	ENSG00000171051	NA	FPR1	formyl peptide receptor 1	2357	ENSG00000171051
9	ENSG00000205403	NA	CFI	complement factor I	3426	ENSG00000205403
10	ENSG00000197405	NA	C5AR1	complement component 5a receptor 1	728	ENSG00000197405
11	ENSG00000159403	NA	C1R	complement component 1, r subcomponent	715	ENSG00000159403
12	ENSG00000136634	NA	IL10	interleukin 10	3586	ENSG00000136634
13	ENSG00000162747	NA	FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	2215	ENSG00000162747
14	ENSG00000203747	NA	FCGR3A	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)	2214	ENSG00000203747
15	ENSG00000186431	NA	FCAR	Fc fragment of IgA, receptor for	2204	ENSG00000186431
16	ENSG00000173369	NA	C1QB	complement component 1, q subcomponent, B chain	713	ENSG00000173369
17	ENSG00000160255	NA	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	3689	ENSG00000160255
18	ENSG00000173372	NA	C1QA	complement component 1, q subcomponent, A chain	712	ENSG00000173372
19	ENSG00000150337	NA	FCGR1A	Fc fragment of IgG, high affinity Ia, receptor (CD64)	2209	ENSG00000150337
20	ENSG00000159189	NA	C1QC	complement component 1, q subcomponent, C chain	714	ENSG00000159189
21	ENSG00000143226	NA	FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	2212	ENSG00000143226
22	ENSG00000182326	NA	C1S	complement component 1, s subcomponent	716	ENSG00000182326
23	ENSG00000187474	NA	FPR3	formyl peptide receptor 3	2359	ENSG00000187474
24	ENSG00000166278	NA	C2	complement component 2	717	ENSG00000166278
25	ENSG00000171049	NA	FPR2	formyl peptide receptor 2	2358	ENSG00000171049
26	ENSG00000171860	NA	C3AR1	complement component 3a receptor 1	719	ENSG00000171860

Database:KEGG pathway       Name:Chemokine signaling pathway       ID:04062
C=189; O=39; E=5.87; R=6.64; rawP=4.58e-21; adjP=2.10e-19
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000167236	NA	CCL23	chemokine (C-C motif) ligand 23	6368	ENSG00000167236
2	ENSG00000172724	NA	CCL19	chemokine (C-C motif) ligand 19	6363	ENSG00000172724
3	ENSG00000126353	NA	CCR7	chemokine (C-C motif) receptor 7	1236	ENSG00000126353
4	ENSG00000254087	NA	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	4067	ENSG00000254087
5	ENSG00000134516	NA	DOCK2	dedicator of cytokinesis 2	1794	ENSG00000134516
6	ENSG00000141968	NA	VAV1	vav 1 guanine nucleotide exchange factor	7409	ENSG00000141968
7	ENSG00000161921	NA	CXCL16	chemokine (C-X-C motif) ligand 16	58191	ENSG00000161921
8	ENSG00000163823	NA	CCR1	chemokine (C-C motif) receptor 1	1230	ENSG00000163823
9	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
10	ENSG00000167083	NA	GNGT2	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2	2793	ENSG00000167083
11	ENSG00000163932	NA	PRKCD	protein kinase C, delta	5580	ENSG00000163932
12	ENSG00000158517	NA	NCF1	neutrophil cytosolic factor 1	653361	ENSG00000158517
13	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
14	ENSG00000138031	NA	ADCY3	adenylate cyclase 3	109	ENSG00000138031
15	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
16	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841
17	ENSG00000114353	NA	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	2771	ENSG00000114353
18	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
19	ENSG00000173578	NA	XCR1	chemokine (C motif) receptor 1	2829	ENSG00000173578
20	ENSG00000163736	NA	PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	5473	ENSG00000163736
21	ENSG00000108688	NA	CCL7	chemokine (C-C motif) ligand 7	6354	ENSG00000108688
22	ENSG00000125388	NA	GRK4	G protein-coupled receptor kinase 4	2868	ENSG00000125388
23	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
24	ENSG00000180871	NA	CXCR2	chemokine (C-X-C motif) receptor 2	3579	ENSG00000180871
25	ENSG00000127314	NA	RAP1B	RAP1B, member of RAS oncogene family	5908	ENSG00000127314
26	ENSG00000124126	NA	PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	57580	ENSG00000124126
27	ENSG00000121807	NA	CCR2	chemokine (C-C motif) receptor 2	729230	ENSG00000121807
28	ENSG00000124875	NA	CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	6372	ENSG00000124875
29	ENSG00000065135	NA	GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	2773	ENSG00000065135
30	ENSG00000101336	NA	HCK	hemopoietic cell kinase	3055	ENSG00000101336
31	ENSG00000015285	NA	WAS	Wiskott-Aldrich syndrome	7454	ENSG00000015285
32	ENSG00000000938	NA	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	2268	ENSG00000000938
33	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
34	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
35	ENSG00000181374	NA	CCL13	chemokine (C-C motif) ligand 13	6357	ENSG00000181374
36	ENSG00000141480	NA	ARRB2	arrestin, beta 2	409	ENSG00000141480
37	ENSG00000105639	NA	JAK3	Janus kinase 3	3718	ENSG00000105639
38	ENSG00000163464	NA	CXCR1	chemokine (C-X-C motif) receptor 1	3577	ENSG00000163464
39	ENSG00000006074	NA	CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	6362	ENSG00000006074

Database:KEGG pathway       Name:Phagosome       ID:04145
C=153; O=33; E=4.75; R=6.94; rawP=1.15e-18; adjP=3.01e-17
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000137267	NA	TUBB2A	tubulin, beta 2A class IIa	7280	ENSG00000137267
2	ENSG00000120586	NA	MRC1	mannose receptor, C type 1	4360	ENSG00000120586
3	ENSG00000169896	NA	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	3684	ENSG00000169896
4	ENSG00000038945	NA	MSR1	macrophage scavenger receptor 1	4481	ENSG00000038945
5	ENSG00000116701	NA	NCF2	neutrophil cytosolic factor 2	4688	ENSG00000116701
6	ENSG00000186431	NA	FCAR	Fc fragment of IgA, receptor for	2204	ENSG00000186431
7	ENSG00000137801	NA	THBS1	thrombospondin 1	7057	ENSG00000137801
8	ENSG00000163131	NA	CTSS	cathepsin S	1520	ENSG00000163131
9	ENSG00000150337	NA	FCGR1A	Fc fragment of IgG, high affinity Ia, receptor (CD64)	2209	ENSG00000150337
10	ENSG00000158517	NA	NCF1	neutrophil cytosolic factor 1	653361	ENSG00000158517
11	ENSG00000102879	NA	CORO1A	coronin, actin binding protein, 1A	11151	ENSG00000102879
12	ENSG00000136869	NA	TLR4	toll-like receptor 4	7099	ENSG00000136869
13	ENSG00000165168	NA	CYBB	cytochrome b-245, beta polypeptide	1536	ENSG00000165168
14	ENSG00000065665	NA	SEC61A2	Sec61 alpha 2 subunit (S. cerevisiae)	55176	ENSG00000065665
15	ENSG00000125730	NA	C3	complement component 3	718	ENSG00000125730
16	ENSG00000072694	NA	FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	2213	ENSG00000072694
17	ENSG00000100365	NA	NCF4	neutrophil cytosolic factor 4, 40kDa	4689	ENSG00000100365
18	ENSG00000172243	NA	CLEC7A	C-type lectin domain family 7, member A	64581	ENSG00000172243
19	ENSG00000144635	NA	DYNC1LI1	dynein, cytoplasmic 1, light intermediate chain 1	51143	ENSG00000144635
20	ENSG00000117758	NA	STX12	syntaxin 12	23673	ENSG00000117758
21	ENSG00000090659	NA	CD209	CD209 molecule	30835	ENSG00000090659
22	ENSG00000159403	NA	C1R	complement component 1, r subcomponent	715	ENSG00000159403
23	ENSG00000170458	NA	CD14	CD14 molecule	929	ENSG00000170458
24	ENSG00000162747	NA	FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	2215	ENSG00000162747
25	ENSG00000174130	NA	TLR6	toll-like receptor 6	10333	ENSG00000174130
26	ENSG00000203747	NA	FCGR3A	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)	2214	ENSG00000203747
27	ENSG00000160255	NA	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	3689	ENSG00000160255
28	ENSG00000019169	NA	MARCO	macrophage receptor with collagenous structure	8685	ENSG00000019169
29	ENSG00000158270	NA	COLEC12	collectin sub-family member 12	81035	ENSG00000158270
30	ENSG00000051523	NA	CYBA	cytochrome b-245, alpha polypeptide	1535	ENSG00000051523
31	ENSG00000164171	NA	ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	3673	ENSG00000164171
32	ENSG00000143226	NA	FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	2212	ENSG00000143226
33	ENSG00000108774	NA	RAB5C	RAB5C, member RAS oncogene family	5878	ENSG00000108774

Database:KEGG pathway       Name:Chagas disease (American trypanosomiasis)       ID:05142
C=104; O=28; E=3.23; R=8.67; rawP=8.62e-19; adjP=3.01e-17
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000125730	NA	C3	complement component 3	718	ENSG00000125730
2	ENSG00000159128	NA	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)	3460	ENSG00000159128
3	ENSG00000060558	NA	GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	2769	ENSG00000060558
4	ENSG00000106799	NA	TGFBR1	transforming growth factor, beta receptor 1	7046	ENSG00000106799
5	ENSG00000136634	NA	IL10	interleukin 10	3586	ENSG00000136634
6	ENSG00000174130	NA	TLR6	toll-like receptor 6	10333	ENSG00000174130
7	ENSG00000065135	NA	GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	2773	ENSG00000065135
8	ENSG00000168040	NA	FADD	Fas (TNFRSF6)-associated via death domain	8772	ENSG00000168040
9	ENSG00000137713	NA	PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	5519	ENSG00000137713
10	ENSG00000026103	NA	FAS	Fas (TNF receptor superfamily, member 6)	355	ENSG00000026103
11	ENSG00000173369	NA	C1QB	complement component 1, q subcomponent, B chain	713	ENSG00000173369
12	ENSG00000087460	NA	GNAS	GNAS complex locus	2778	ENSG00000087460
13	ENSG00000173372	NA	C1QA	complement component 1, q subcomponent, A chain	712	ENSG00000173372
14	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
15	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
16	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
17	ENSG00000159189	NA	C1QC	complement component 1, q subcomponent, C chain	714	ENSG00000159189
18	ENSG00000198001	NA	IRAK4	interleukin-1 receptor-associated kinase 4	51135	ENSG00000198001
19	ENSG00000067182	NA	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	7132	ENSG00000067182
20	ENSG00000156052	NA	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	2776	ENSG00000156052
21	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
22	ENSG00000106366	NA	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	5054	ENSG00000106366
23	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
24	ENSG00000172936	NA	MYD88	myeloid differentiation primary response gene (88)	4615	ENSG00000172936
25	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841
26	ENSG00000136869	NA	TLR4	toll-like receptor 4	7099	ENSG00000136869
27	ENSG00000114353	NA	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	2771	ENSG00000114353
28	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039

Database:KEGG pathway       Name:Leishmaniasis       ID:05140
C=72; O=24; E=2.24; R=10.73; rawP=1.02e-18; adjP=3.01e-17
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000125730	NA	C3	complement component 3	718	ENSG00000125730
2	ENSG00000100365	NA	NCF4	neutrophil cytosolic factor 4, 40kDa	4689	ENSG00000100365
3	ENSG00000159128	NA	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)	3460	ENSG00000159128
4	ENSG00000111679	NA	PTPN6	protein tyrosine phosphatase, non-receptor type 6	5777	ENSG00000111679
5	ENSG00000115232	NA	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	3676	ENSG00000115232
6	ENSG00000169896	NA	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	3684	ENSG00000169896
7	ENSG00000175130	NA	MARCKSL1	MARCKS-like 1	65108	ENSG00000175130
8	ENSG00000136634	NA	IL10	interleukin 10	3586	ENSG00000136634
9	ENSG00000162747	NA	FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	2215	ENSG00000162747
10	ENSG00000116701	NA	NCF2	neutrophil cytosolic factor 2	4688	ENSG00000116701
11	ENSG00000203747	NA	FCGR3A	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)	2214	ENSG00000203747
12	ENSG00000160255	NA	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	3689	ENSG00000160255
13	ENSG00000051523	NA	CYBA	cytochrome b-245, alpha polypeptide	1535	ENSG00000051523
14	ENSG00000150337	NA	FCGR1A	Fc fragment of IgG, high affinity Ia, receptor (CD64)	2209	ENSG00000150337
15	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
16	ENSG00000203710	NA	CR1	complement component (3b/4b) receptor 1 (Knops blood group)	1378	ENSG00000203710
17	ENSG00000158517	NA	NCF1	neutrophil cytosolic factor 1	653361	ENSG00000158517
18	ENSG00000198001	NA	IRAK4	interleukin-1 receptor-associated kinase 4	51135	ENSG00000198001
19	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
20	ENSG00000143226	NA	FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	2212	ENSG00000143226
21	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
22	ENSG00000172936	NA	MYD88	myeloid differentiation primary response gene (88)	4615	ENSG00000172936
23	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
24	ENSG00000136869	NA	TLR4	toll-like receptor 4	7099	ENSG00000136869

Database:KEGG pathway       Name:B cell receptor signaling pathway       ID:04662
C=75; O=23; E=2.33; R=9.87; rawP=4.46e-17; adjP=1.02e-15
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000072694	NA	FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	2213	ENSG00000072694
2	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
3	ENSG00000146232	NA	NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	4794	ENSG00000146232
4	ENSG00000111679	NA	PTPN6	protein tyrosine phosphatase, non-receptor type 6	5777	ENSG00000111679
5	ENSG00000168918	NA	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	3635	ENSG00000168918
6	ENSG00000010671	NA	BTK	Bruton agammaglobulinemia tyrosine kinase	695	ENSG00000010671
7	ENSG00000107758	NA	PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	5532	ENSG00000107758
8	ENSG00000137101	NA	CD72	CD72 molecule	971	ENSG00000137101
9	ENSG00000254087	NA	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	4067	ENSG00000254087
10	ENSG00000095585	NA	BLNK	B-cell linker	29760	ENSG00000095585
11	ENSG00000141968	NA	VAV1	vav 1 guanine nucleotide exchange factor	7409	ENSG00000141968
12	ENSG00000105369	NA	CD79A	CD79a molecule, immunoglobulin-associated alpha	973	ENSG00000105369
13	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
14	ENSG00000155629	NA	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1	118788	ENSG00000155629
15	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
16	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
17	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
18	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
19	ENSG00000070190	NA	DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	27071	ENSG00000070190
20	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
21	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
22	ENSG00000204577	NA	LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	11025	ENSG00000204577
23	ENSG00000165025	NA	SYK	spleen tyrosine kinase	6850	ENSG00000165025

Database:KEGG pathway       Name:Complement and coagulation cascades       ID:04610
C=69; O=22; E=2.14; R=10.26; rawP=8.38e-17; adjP=1.70e-15
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000224389	NA	C4B	complement component 4B (Chido blood group)	721	ENSG00000224389
2	ENSG00000125730	NA	C3	complement component 3	718	ENSG00000125730
3	ENSG00000244731	NA	C4A	complement component 4A (Rodgers blood group)	720	ENSG00000244731
4	ENSG00000003436	NA	TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	7035	ENSG00000003436
5	ENSG00000205403	NA	CFI	complement factor I	3426	ENSG00000205403
6	ENSG00000124491	NA	F13A1	coagulation factor XIII, A1 polypeptide	2162	ENSG00000124491
7	ENSG00000197405	NA	C5AR1	complement component 5a receptor 1	728	ENSG00000197405
8	ENSG00000159403	NA	C1R	complement component 1, r subcomponent	715	ENSG00000159403
9	ENSG00000112936	NA	C7	complement component 7	730	ENSG00000112936
10	ENSG00000123843	NA	C4BPB	complement component 4 binding protein, beta	725	ENSG00000123843
11	ENSG00000173369	NA	C1QB	complement component 1, q subcomponent, B chain	713	ENSG00000173369
12	ENSG00000188488	NA	SERPINA5	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	5104	ENSG00000188488
13	ENSG00000197249	NA	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	5265	ENSG00000197249
14	ENSG00000173372	NA	C1QA	complement component 1, q subcomponent, A chain	712	ENSG00000173372
15	ENSG00000149131	NA	SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	710	ENSG00000149131
16	ENSG00000203710	NA	CR1	complement component (3b/4b) receptor 1 (Knops blood group)	1378	ENSG00000203710
17	ENSG00000159189	NA	C1QC	complement component 1, q subcomponent, C chain	714	ENSG00000159189
18	ENSG00000182326	NA	C1S	complement component 1, s subcomponent	716	ENSG00000182326
19	ENSG00000106366	NA	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	5054	ENSG00000106366
20	ENSG00000166278	NA	C2	complement component 2	717	ENSG00000166278
21	ENSG00000167711	NA	SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	5345	ENSG00000167711
22	ENSG00000171860	NA	C3AR1	complement component 3a receptor 1	719	ENSG00000171860

Database:KEGG pathway       Name:Fc gamma R-mediated phagocytosis       ID:04666
C=94; O=24; E=2.92; R=8.22; rawP=9.80e-16; adjP=1.79e-14
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000072694	NA	FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	2213	ENSG00000072694
2	ENSG00000112290	NA	WASF1	WAS protein family, member 1	8936	ENSG00000112290
3	ENSG00000168918	NA	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	3635	ENSG00000168918
4	ENSG00000175130	NA	MARCKSL1	MARCKS-like 1	65108	ENSG00000175130
5	ENSG00000254087	NA	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	4067	ENSG00000254087
6	ENSG00000101336	NA	HCK	hemopoietic cell kinase	3055	ENSG00000101336
7	ENSG00000134516	NA	DOCK2	dedicator of cytokinesis 2	1794	ENSG00000134516
8	ENSG00000203747	NA	FCGR3A	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)	2214	ENSG00000203747
9	ENSG00000141968	NA	VAV1	vav 1 guanine nucleotide exchange factor	7409	ENSG00000141968
10	ENSG00000081237	NA	PTPRC	protein tyrosine phosphatase, receptor type, C	5788	ENSG00000081237
11	ENSG00000015285	NA	WAS	Wiskott-Aldrich syndrome	7454	ENSG00000015285
12	ENSG00000130429	NA	ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	10095	ENSG00000130429
13	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
14	ENSG00000162704	NA	ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	10092	ENSG00000162704
15	ENSG00000150337	NA	FCGR1A	Fc fragment of IgG, high affinity Ia, receptor (CD64)	2209	ENSG00000150337
16	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
17	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
18	ENSG00000163932	NA	PRKCD	protein kinase C, delta	5580	ENSG00000163932
19	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
20	ENSG00000158517	NA	NCF1	neutrophil cytosolic factor 1	653361	ENSG00000158517
21	ENSG00000143226	NA	FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	2212	ENSG00000143226
22	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
23	ENSG00000165527	NA	ARF6	ADP-ribosylation factor 6	382	ENSG00000165527
24	ENSG00000165025	NA	SYK	spleen tyrosine kinase	6850	ENSG00000165025

Database:KEGG pathway       Name:Metabolic pathways       ID:01100
C=1130; O=88; E=35.11; R=2.51; rawP=4.52e-15; adjP=7.52e-14
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000131459	NA	GFPT2	glutamine-fructose-6-phosphate transaminase 2	9945	ENSG00000131459
2	ENSG00000178802	NA	MPI	mannose phosphate isomerase	4351	ENSG00000178802
3	ENSG00000198682	NA	PAPSS2	3'-phosphoadenosine 5'-phosphosulfate synthase 2	9060	ENSG00000198682
4	ENSG00000148154	NA	UGCG	UDP-glucose ceramide glucosyltransferase	7357	ENSG00000148154
5	ENSG00000087253	NA	LPCAT2	lysophosphatidylcholine acyltransferase 2	54947	ENSG00000087253
6	ENSG00000139629	NA	GALNT6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)	11226	ENSG00000139629
7	ENSG00000109814	NA	UGDH	UDP-glucose 6-dehydrogenase	7358	ENSG00000109814
8	ENSG00000139163	NA	ETNK1	ethanolamine kinase 1	55500	ENSG00000139163
9	ENSG00000060982	NA	BCAT1	branched chain amino-acid transaminase 1, cytosolic	586	ENSG00000060982
10	ENSG00000183044	NA	ABAT	4-aminobutyrate aminotransferase	18	ENSG00000183044
11	ENSG00000118520	NA	ARG1	arginase, liver	383	ENSG00000118520
12	ENSG00000163803	NA	PLB1	phospholipase B1	151056	ENSG00000163803
13	ENSG00000196616	NA	ADH1B	alcohol dehydrogenase 1B (class I), beta polypeptide	125	ENSG00000196616
14	ENSG00000241878	NA	PISD	phosphatidylserine decarboxylase	23761	ENSG00000241878
15	ENSG00000163624	NA	CDS1	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1	1040	ENSG00000163624
16	ENSG00000012779	NA	ALOX5	arachidonate 5-lipoxygenase	240	ENSG00000012779
17	ENSG00000133805	NA	AMPD3	adenosine monophosphate deaminase 3	272	ENSG00000133805
18	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
19	ENSG00000184254	NA	ALDH1A3	aldehyde dehydrogenase 1 family, member A3	220	ENSG00000184254
20	ENSG00000112893	NA	MAN2A1	mannosidase, alpha, class 2A, member 1	4124	ENSG00000112893
21	ENSG00000138356	NA	AOX1	aldehyde oxidase 1	316	ENSG00000138356
22	ENSG00000188641	NA	DPYD	dihydropyrimidine dehydrogenase	1806	ENSG00000188641
23	ENSG00000090054	NA	SPTLC1	serine palmitoyltransferase, long chain base subunit 1	10558	ENSG00000090054
24	ENSG00000242110	NA	AMACR	alpha-methylacyl-CoA racemase	23600	ENSG00000242110
25	ENSG00000074416	NA	MGLL	monoglyceride lipase	11343	ENSG00000074416
26	ENSG00000163738	NA	MTHFD2L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like	441024	ENSG00000163738
27	ENSG00000130414	NA	NDUFA10	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa	4705	ENSG00000130414
28	ENSG00000197142	NA	ACSL5	acyl-CoA synthetase long-chain family member 5	51703	ENSG00000197142
29	ENSG00000111846	NA	GCNT2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)	2651	ENSG00000111846
30	ENSG00000146070	NA	PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	7941	ENSG00000146070
31	ENSG00000131238	NA	PPT1	palmitoyl-protein thioesterase 1	5538	ENSG00000131238
32	ENSG00000130066	NA	SAT1	spermidine/spermine N1-acetyltransferase 1	6303	ENSG00000130066
33	ENSG00000104951	NA	IL4I1	interleukin 4 induced 1	259307	ENSG00000104951
34	ENSG00000115525	NA	ST3GAL5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	8869	ENSG00000115525
35	ENSG00000186529	NA	CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	4051	ENSG00000186529
36	ENSG00000166825	NA	ANPEP	alanyl (membrane) aminopeptidase	290	ENSG00000166825
37	ENSG00000079462	NA	PAFAH1B3	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)	5050	ENSG00000079462
38	ENSG00000173083	NA	HPSE	heparanase	10855	ENSG00000173083
39	ENSG00000135094	NA	SDS	serine dehydratase	10993	ENSG00000135094
40	ENSG00000124212	NA	PTGIS	prostaglandin I2 (prostacyclin) synthase	5740	ENSG00000124212
41	ENSG00000115919	NA	KYNU	kynureninase	8942	ENSG00000115919
42	ENSG00000165140	NA	FBP1	fructose-1,6-bisphosphatase 1	2203	ENSG00000165140
43	ENSG00000160211	NA	G6PD	glucose-6-phosphate dehydrogenase	2539	ENSG00000160211
44	ENSG00000023330	NA	ALAS1	aminolevulinate, delta-, synthase 1	211	ENSG00000023330
45	ENSG00000140287	NA	HDC	histidine decarboxylase	3067	ENSG00000140287
46	ENSG00000067057	NA	PFKP	phosphofructokinase, platelet	5214	ENSG00000067057
47	ENSG00000111726	NA	CMAS	cytidine monophosphate N-acetylneuraminic acid synthetase	55907	ENSG00000111726
48	ENSG00000166741	NA	NNMT	nicotinamide N-methyltransferase	4837	ENSG00000166741
49	ENSG00000140263	NA	SORD	sorbitol dehydrogenase	6652	ENSG00000140263
50	ENSG00000102967	NA	DHODH	dihydroorotate dehydrogenase (quinone)	1723	ENSG00000102967
51	ENSG00000131873	NA	CHSY1	chondroitin sulfate synthase 1	22856	ENSG00000131873
52	ENSG00000140650	NA	PMM2	phosphomannomutase 2	5373	ENSG00000140650
53	ENSG00000163106	NA	HPGDS	hematopoietic prostaglandin D synthase	27306	ENSG00000163106
54	ENSG00000196839	NA	ADA	adenosine deaminase	100	ENSG00000196839
55	ENSG00000111885	NA	MAN1A1	mannosidase, alpha, class 1A, member 1	4121	ENSG00000111885
56	ENSG00000131446	NA	MGAT1	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	4245	ENSG00000131446
57	ENSG00000117594	NA	HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	3290	ENSG00000117594
58	ENSG00000129596	NA	CDO1	cysteine dioxygenase, type I	1036	ENSG00000129596
59	ENSG00000095303	NA	PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	5742	ENSG00000095303
60	ENSG00000143811	NA	PYCR2	pyrroline-5-carboxylate reductase family, member 2	29920	ENSG00000143811
61	ENSG00000100889	NA	PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	5106	ENSG00000100889
62	ENSG00000160883	NA	HK3	hexokinase 3 (white cell)	3101	ENSG00000160883
63	ENSG00000153395	NA	LPCAT1	lysophosphatidylcholine acyltransferase 1	79888	ENSG00000153395
64	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841
65	ENSG00000187210	NA	GCNT1	glucosaminyl (N-acetyl) transferase 1, core 2	2650	ENSG00000187210
66	ENSG00000143149	NA	ALDH9A1	aldehyde dehydrogenase 9 family, member A1	223	ENSG00000143149
67	ENSG00000133731	NA	IMPA1	inositol(myo)-1(or 4)-monophosphatase 1	3612	ENSG00000133731
68	ENSG00000001084	NA	GCLC	glutamate-cysteine ligase, catalytic subunit	2729	ENSG00000001084
69	ENSG00000127472	NA	PLA2G5	phospholipase A2, group V	5322	ENSG00000127472
70	ENSG00000059377	NA	TBXAS1	thromboxane A synthase 1 (platelet)	6916	ENSG00000059377
71	ENSG00000185274	NA	WBSCR17	Williams-Beuren syndrome chromosome region 17	64409	ENSG00000185274
72	ENSG00000101638	NA	ST8SIA5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5	29906	ENSG00000101638
73	ENSG00000077514	NA	POLD3	polymerase (DNA-directed), delta 3, accessory subunit	10714	ENSG00000077514
74	ENSG00000185133	NA	INPP5J	inositol polyphosphate-5-phosphatase J	27124	ENSG00000185133
75	ENSG00000100596	NA	SPTLC2	serine palmitoyltransferase, long chain base subunit 2	9517	ENSG00000100596
76	ENSG00000188257	NA	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	5320	ENSG00000188257
77	ENSG00000142657	NA	PGD	phosphogluconate dehydrogenase	5226	ENSG00000142657
78	ENSG00000115339	NA	GALNT3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)	2591	ENSG00000115339
79	ENSG00000120697	NA	ALG5	asparagine-linked glycosylation 5, dolichyl-phosphate beta-glucosyltransferase homolog (S. cerevisiae)	29880	ENSG00000120697
80	ENSG00000006530	NA	AGK	acylglycerol kinase	55750	ENSG00000006530
81	ENSG00000117143	NA	UAP1	UDP-N-acteylglucosamine pyrophosphorylase 1	6675	ENSG00000117143
82	ENSG00000101911	NA	PRPS2	phosphoribosyl pyrophosphate synthetase 2	5634	ENSG00000101911
83	ENSG00000106348	NA	IMPDH1	IMP (inosine 5'-monophosphate) dehydrogenase 1	3614	ENSG00000106348
84	ENSG00000170266	NA	GLB1	galactosidase, beta 1	2720	ENSG00000170266
85	ENSG00000117054	NA	ACADM	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	34	ENSG00000117054
86	ENSG00000119523	NA	ALG2	asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae)	85365	ENSG00000119523
87	ENSG00000131067	NA	GGT7	gamma-glutamyltransferase 7	2686	ENSG00000131067
88	ENSG00000148344	NA	PTGES	prostaglandin E synthase	9536	ENSG00000148344

Database:KEGG pathway       Name:Apoptosis       ID:04210
C=87; O=21; E=2.70; R=7.77; rawP=2.02e-13; adjP=3.08e-12
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000138794	NA	CASP6	caspase 6, apoptosis-related cysteine peptidase	839	ENSG00000138794
2	ENSG00000120889	NA	TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	8795	ENSG00000120889
3	ENSG00000141510	NA	TP53	tumor protein p53	7157	ENSG00000141510
4	ENSG00000137275	NA	RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	8737	ENSG00000137275
5	ENSG00000107758	NA	PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	5532	ENSG00000107758
6	ENSG00000173535	NA	TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	8794	ENSG00000173535
7	ENSG00000168040	NA	FADD	Fas (TNFRSF6)-associated via death domain	8772	ENSG00000168040
8	ENSG00000026103	NA	FAS	Fas (TNF receptor superfamily, member 6)	355	ENSG00000026103
9	ENSG00000115594	NA	IL1R1	interleukin 1 receptor, type I	3554	ENSG00000115594
10	ENSG00000100368	NA	CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	1439	ENSG00000100368
11	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
12	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
13	ENSG00000134070	NA	IRAK2	interleukin-1 receptor-associated kinase 2	3656	ENSG00000134070
14	ENSG00000198001	NA	IRAK4	interleukin-1 receptor-associated kinase 4	51135	ENSG00000198001
15	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
16	ENSG00000067182	NA	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	7132	ENSG00000067182
17	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
18	ENSG00000120868	NA	APAF1	apoptotic peptidase activating factor 1	317	ENSG00000120868
19	ENSG00000172936	NA	MYD88	myeloid differentiation primary response gene (88)	4615	ENSG00000172936
20	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
21	ENSG00000108946	NA	PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha	5573	ENSG00000108946

Database:KEGG pathway       Name:Hematopoietic cell lineage       ID:04640
C=88; O=21; E=2.73; R=7.68; rawP=2.57e-13; adjP=3.62e-12
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000104432	NA	IL7	interleukin 7	3574	ENSG00000104432
2	ENSG00000010610	NA	CD4	CD4 molecule	920	ENSG00000010610
3	ENSG00000115232	NA	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	3676	ENSG00000115232
4	ENSG00000198223	NA	CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	1438	ENSG00000198223
5	ENSG00000169896	NA	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	3684	ENSG00000169896
6	ENSG00000170458	NA	CD14	CD14 molecule	929	ENSG00000170458
7	ENSG00000005961	NA	ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	3674	ENSG00000005961
8	ENSG00000166825	NA	ANPEP	alanyl (membrane) aminopeptidase	290	ENSG00000166825
9	ENSG00000119535	NA	CSF3R	colony stimulating factor 3 receptor (granulocyte)	1441	ENSG00000119535
10	ENSG00000115594	NA	IL1R1	interleukin 1 receptor, type I	3554	ENSG00000115594
11	ENSG00000104894	NA	CD37	CD37 molecule	951	ENSG00000104894
12	ENSG00000150337	NA	FCGR1A	Fc fragment of IgG, high affinity Ia, receptor (CD64)	2209	ENSG00000150337
13	ENSG00000203710	NA	CR1	complement component (3b/4b) receptor 1 (Knops blood group)	1378	ENSG00000203710
14	ENSG00000184371	NA	CSF1	colony stimulating factor 1 (macrophage)	1435	ENSG00000184371
15	ENSG00000164171	NA	ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	3673	ENSG00000164171
16	ENSG00000115590	NA	IL1R2	interleukin 1 receptor, type II	7850	ENSG00000115590
17	ENSG00000077238	NA	IL4R	interleukin 4 receptor	3566	ENSG00000077238
18	ENSG00000134460	NA	IL2RA	interleukin 2 receptor, alpha	3559	ENSG00000134460
19	ENSG00000026508	NA	CD44	CD44 molecule (Indian blood group)	960	ENSG00000026508
20	ENSG00000105383	NA	CD33	CD33 molecule	945	ENSG00000105383
21	ENSG00000182578	NA	CSF1R	colony stimulating factor 1 receptor	1436	ENSG00000182578

Database:KEGG pathway       Name:Jak-STAT signaling pathway       ID:04630
C=155; O=27; E=4.82; R=5.61; rawP=3.84e-13; adjP=5.02e-12
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000104432	NA	IL7	interleukin 7	3574	ENSG00000104432
2	ENSG00000159128	NA	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)	3460	ENSG00000159128
3	ENSG00000134470	NA	IL15RA	interleukin 15 receptor, alpha	3601	ENSG00000134470
4	ENSG00000111679	NA	PTPN6	protein tyrosine phosphatase, non-receptor type 6	5777	ENSG00000111679
5	ENSG00000198223	NA	CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	1438	ENSG00000198223
6	ENSG00000175505	NA	CLCF1	cardiotrophin-like cytokine factor 1	23529	ENSG00000175505
7	ENSG00000174564	NA	IL20RB	interleukin 20 receptor beta	53833	ENSG00000174564
8	ENSG00000131724	NA	IL13RA1	interleukin 13 receptor, alpha 1	3597	ENSG00000131724
9	ENSG00000096996	NA	IL12RB1	interleukin 12 receptor, beta 1	3594	ENSG00000096996
10	ENSG00000136634	NA	IL10	interleukin 10	3586	ENSG00000136634
11	ENSG00000110944	NA	IL23A	interleukin 23, alpha subunit p19	51561	ENSG00000110944
12	ENSG00000110324	NA	IL10RA	interleukin 10 receptor, alpha	3587	ENSG00000110324
13	ENSG00000119535	NA	CSF3R	colony stimulating factor 3 receptor (granulocyte)	1441	ENSG00000119535
14	ENSG00000100368	NA	CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	1439	ENSG00000100368
15	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
16	ENSG00000134352	NA	IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	3572	ENSG00000134352
17	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
18	ENSG00000162892	NA	IL24	interleukin 24	11009	ENSG00000162892
19	ENSG00000145623	NA	OSMR	oncostatin M receptor	9180	ENSG00000145623
20	ENSG00000150281	NA	CTF1	cardiotrophin 1	1489	ENSG00000150281
21	ENSG00000126561	NA	STAT5A	signal transducer and activator of transcription 5A	6776	ENSG00000126561
22	ENSG00000134460	NA	IL2RA	interleukin 2 receptor, alpha	3559	ENSG00000134460
23	ENSG00000077238	NA	IL4R	interleukin 4 receptor	3566	ENSG00000077238
24	ENSG00000187678	NA	SPRY4	sprouty homolog 4 (Drosophila)	81848	ENSG00000187678
25	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
26	ENSG00000118971	NA	CCND2	cyclin D2	894	ENSG00000118971
27	ENSG00000105639	NA	JAK3	Janus kinase 3	3718	ENSG00000105639

Database:KEGG pathway       Name:Toll-like receptor signaling pathway       ID:04620
C=102; O=21; E=3.17; R=6.63; rawP=5.54e-12; adjP=6.76e-11
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000183735	NA	TBK1	TANK-binding kinase 1	29110	ENSG00000183735
2	ENSG00000114013	NA	CD86	CD86 molecule	942	ENSG00000114013
3	ENSG00000137275	NA	RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	8737	ENSG00000137275
4	ENSG00000170458	NA	CD14	CD14 molecule	929	ENSG00000170458
5	ENSG00000174130	NA	TLR6	toll-like receptor 6	10333	ENSG00000174130
6	ENSG00000128604	NA	IRF5	interferon regulatory factor 5	3663	ENSG00000128604
7	ENSG00000101916	NA	TLR8	toll-like receptor 8	51311	ENSG00000101916
8	ENSG00000168040	NA	FADD	Fas (TNFRSF6)-associated via death domain	8772	ENSG00000168040
9	ENSG00000118785	NA	SPP1	secreted phosphoprotein 1	6696	ENSG00000118785
10	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
11	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
12	ENSG00000198001	NA	IRAK4	interleukin-1 receptor-associated kinase 4	51135	ENSG00000198001
13	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
14	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
15	ENSG00000154589	NA	LY96	lymphocyte antigen 96	23643	ENSG00000154589
16	ENSG00000129988	NA	LBP	lipopolysaccharide binding protein	3929	ENSG00000129988
17	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
18	ENSG00000172936	NA	MYD88	myeloid differentiation primary response gene (88)	4615	ENSG00000172936
19	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
20	ENSG00000136869	NA	TLR4	toll-like receptor 4	7099	ENSG00000136869
21	ENSG00000174125	NA	TLR1	toll-like receptor 1	7096	ENSG00000174125

Database:KEGG pathway       Name:Leukocyte transendothelial migration       ID:04670
C=116; O=22; E=3.60; R=6.10; rawP=9.84e-12; adjP=1.13e-10
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000100985	NA	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	4318	ENSG00000100985
2	ENSG00000002586	NA	CD99	CD99 molecule	4267	ENSG00000002586
3	ENSG00000100365	NA	NCF4	neutrophil cytosolic factor 4, 40kDa	4689	ENSG00000100365
4	ENSG00000115232	NA	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	3676	ENSG00000115232
5	ENSG00000169896	NA	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	3684	ENSG00000169896
6	ENSG00000127314	NA	RAP1B	RAP1B, member of RAS oncogene family	5908	ENSG00000127314
7	ENSG00000136653	NA	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	83593	ENSG00000136653
8	ENSG00000158769	NA	F11R	F11 receptor	50848	ENSG00000158769
9	ENSG00000065135	NA	GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	2773	ENSG00000065135
10	ENSG00000116701	NA	NCF2	neutrophil cytosolic factor 2	4688	ENSG00000116701
11	ENSG00000141968	NA	VAV1	vav 1 guanine nucleotide exchange factor	7409	ENSG00000141968
12	ENSG00000160255	NA	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	3689	ENSG00000160255
13	ENSG00000051523	NA	CYBA	cytochrome b-245, alpha polypeptide	1535	ENSG00000051523
14	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
15	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
16	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
17	ENSG00000158517	NA	NCF1	neutrophil cytosolic factor 1	653361	ENSG00000158517
18	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
19	ENSG00000162692	NA	VCAM1	vascular cell adhesion molecule 1	7412	ENSG00000162692
20	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
21	ENSG00000114353	NA	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	2771	ENSG00000114353
22	ENSG00000165168	NA	CYBB	cytochrome b-245, beta polypeptide	1536	ENSG00000165168

Database:KEGG pathway       Name:Amoebiasis       ID:05146
C=106; O=21; E=3.29; R=6.38; rawP=1.21e-11; adjP=1.30e-10
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000135862	NA	LAMC1	laminin, gamma 1 (formerly LAMB2)	3915	ENSG00000135862
2	ENSG00000060558	NA	GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	2769	ENSG00000060558
3	ENSG00000081052	NA	COL4A4	collagen, type IV, alpha 4	1286	ENSG00000081052
4	ENSG00000169896	NA	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	3684	ENSG00000169896
5	ENSG00000170542	NA	SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	5272	ENSG00000170542
6	ENSG00000170458	NA	CD14	CD14 molecule	929	ENSG00000170458
7	ENSG00000136634	NA	IL10	interleukin 10	3586	ENSG00000136634
8	ENSG00000118520	NA	ARG1	arginase, liver	383	ENSG00000118520
9	ENSG00000087460	NA	GNAS	GNAS complex locus	2778	ENSG00000087460
10	ENSG00000115594	NA	IL1R1	interleukin 1 receptor, type I	3554	ENSG00000115594
11	ENSG00000160255	NA	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	3689	ENSG00000160255
12	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
13	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
14	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
15	ENSG00000115590	NA	IL1R2	interleukin 1 receptor, type II	7850	ENSG00000115590
16	ENSG00000156052	NA	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	2776	ENSG00000156052
17	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
18	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
19	ENSG00000136869	NA	TLR4	toll-like receptor 4	7099	ENSG00000136869
20	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841
21	ENSG00000108774	NA	RAB5C	RAB5C, member RAS oncogene family	5878	ENSG00000108774

Database:KEGG pathway       Name:Pathways in cancer       ID:05200
C=326; O=35; E=10.13; R=3.46; rawP=2.49e-10; adjP=2.42e-09
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000100985	NA	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	4318	ENSG00000100985
2	ENSG00000177283	NA	FZD8	frizzled family receptor 8	8325	ENSG00000177283
3	ENSG00000141510	NA	TP53	tumor protein p53	7157	ENSG00000141510
4	ENSG00000106799	NA	TGFBR1	transforming growth factor, beta receptor 1	7046	ENSG00000106799
5	ENSG00000124762	NA	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	1026	ENSG00000124762
6	ENSG00000134954	NA	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	2113	ENSG00000134954
7	ENSG00000134853	NA	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	5156	ENSG00000134853
8	ENSG00000005961	NA	ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	3674	ENSG00000005961
9	ENSG00000119535	NA	CSF3R	colony stimulating factor 3 receptor (granulocyte)	1441	ENSG00000119535
10	ENSG00000097007	NA	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	25	ENSG00000097007
11	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
12	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
13	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
14	ENSG00000017427	NA	IGF1	insulin-like growth factor 1 (somatomedin C)	3479	ENSG00000017427
15	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
16	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
17	ENSG00000066336	NA	SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	6688	ENSG00000066336
18	ENSG00000113721	NA	PDGFRB	platelet-derived growth factor receptor, beta polypeptide	5159	ENSG00000113721
19	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
20	ENSG00000131759	NA	RARA	retinoic acid receptor, alpha	5914	ENSG00000131759
21	ENSG00000135862	NA	LAMC1	laminin, gamma 1 (formerly LAMB2)	3915	ENSG00000135862
22	ENSG00000198223	NA	CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	1438	ENSG00000198223
23	ENSG00000081052	NA	COL4A4	collagen, type IV, alpha 4	1286	ENSG00000081052
24	ENSG00000136653	NA	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	83593	ENSG00000136653
25	ENSG00000196611	NA	MMP1	matrix metallopeptidase 1 (interstitial collagenase)	4312	ENSG00000196611
26	ENSG00000168040	NA	FADD	Fas (TNFRSF6)-associated via death domain	8772	ENSG00000168040
27	ENSG00000026103	NA	FAS	Fas (TNF receptor superfamily, member 6)	355	ENSG00000026103
28	ENSG00000112033	NA	PPARD	peroxisome proliferator-activated receptor delta	5467	ENSG00000112033
29	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
30	ENSG00000100644	NA	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	3091	ENSG00000100644
31	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
32	ENSG00000164171	NA	ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	3673	ENSG00000164171
33	ENSG00000126561	NA	STAT5A	signal transducer and activator of transcription 5A	6776	ENSG00000126561
34	ENSG00000101109	NA	STK4	serine/threonine kinase 4	6789	ENSG00000101109
35	ENSG00000182578	NA	CSF1R	colony stimulating factor 1 receptor	1436	ENSG00000182578

Database:KEGG pathway       Name:Systemic lupus erythematosus       ID:05322
C=136; O=22; E=4.23; R=5.21; rawP=2.51e-10; adjP=2.42e-09
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000224389	NA	C4B	complement component 4B (Chido blood group)	721	ENSG00000224389
2	ENSG00000125730	NA	C3	complement component 3	718	ENSG00000125730
3	ENSG00000072694	NA	FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	2213	ENSG00000072694
4	ENSG00000198518	NA	HIST1H4E	histone cluster 1, H4e	8367	ENSG00000198518
5	ENSG00000114013	NA	CD86	CD86 molecule	942	ENSG00000114013
6	ENSG00000244731	NA	C4A	complement component 4A (Rodgers blood group)	720	ENSG00000244731
7	ENSG00000197903	NA	HIST1H2BK	histone cluster 1, H2bk	85236	ENSG00000197903
8	ENSG00000159403	NA	C1R	complement component 1, r subcomponent	715	ENSG00000159403
9	ENSG00000197561	NA	ELANE	elastase, neutrophil expressed	1991	ENSG00000197561
10	ENSG00000136634	NA	IL10	interleukin 10	3586	ENSG00000136634
11	ENSG00000162747	NA	FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	2215	ENSG00000162747
12	ENSG00000112936	NA	C7	complement component 7	730	ENSG00000112936
13	ENSG00000203747	NA	FCGR3A	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)	2214	ENSG00000203747
14	ENSG00000173369	NA	C1QB	complement component 1, q subcomponent, B chain	713	ENSG00000173369
15	ENSG00000173372	NA	C1QA	complement component 1, q subcomponent, A chain	712	ENSG00000173372
16	ENSG00000150337	NA	FCGR1A	Fc fragment of IgG, high affinity Ia, receptor (CD64)	2209	ENSG00000150337
17	ENSG00000159189	NA	C1QC	complement component 1, q subcomponent, C chain	714	ENSG00000159189
18	ENSG00000143226	NA	FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	2212	ENSG00000143226
19	ENSG00000182326	NA	C1S	complement component 1, s subcomponent	716	ENSG00000182326
20	ENSG00000099284	NA	H2AFY2	H2A histone family, member Y2	55506	ENSG00000099284
21	ENSG00000166278	NA	C2	complement component 2	717	ENSG00000166278
22	ENSG00000178562	NA	CD28	CD28 molecule	940	ENSG00000178562

Database:KEGG pathway       Name:Fc epsilon RI signaling pathway       ID:04664
C=79; O=17; E=2.45; R=6.93; rawP=2.75e-10; adjP=2.52e-09
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
2	ENSG00000158869	NA	FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	2207	ENSG00000158869
3	ENSG00000168918	NA	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	3635	ENSG00000168918
4	ENSG00000127472	NA	PLA2G5	phospholipase A2, group V	5322	ENSG00000127472
5	ENSG00000010671	NA	BTK	Bruton agammaglobulinemia tyrosine kinase	695	ENSG00000010671
6	ENSG00000043462	NA	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	3937	ENSG00000043462
7	ENSG00000254087	NA	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	4067	ENSG00000254087
8	ENSG00000188257	NA	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	5320	ENSG00000188257
9	ENSG00000141968	NA	VAV1	vav 1 guanine nucleotide exchange factor	7409	ENSG00000141968
10	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
11	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
12	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
13	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
14	ENSG00000163932	NA	PRKCD	protein kinase C, delta	5580	ENSG00000163932
15	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
16	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
17	ENSG00000165025	NA	SYK	spleen tyrosine kinase	6850	ENSG00000165025

Database:KEGG pathway       Name:Toxoplasmosis       ID:05145
C=132; O=20; E=4.10; R=4.88; rawP=5.23e-09; adjP=4.56e-08
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000135862	NA	LAMC1	laminin, gamma 1 (formerly LAMB2)	3915	ENSG00000135862
2	ENSG00000159128	NA	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)	3460	ENSG00000159128
3	ENSG00000127472	NA	PLA2G5	phospholipase A2, group V	5322	ENSG00000127472
4	ENSG00000136634	NA	IL10	interleukin 10	3586	ENSG00000136634
5	ENSG00000065135	NA	GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	2773	ENSG00000065135
6	ENSG00000110324	NA	IL10RA	interleukin 10 receptor, alpha	3587	ENSG00000110324
7	ENSG00000188257	NA	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	5320	ENSG00000188257
8	ENSG00000012779	NA	ALOX5	arachidonate 5-lipoxygenase	240	ENSG00000012779
9	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
10	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
11	ENSG00000198001	NA	IRAK4	interleukin-1 receptor-associated kinase 4	51135	ENSG00000198001
12	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
13	ENSG00000067182	NA	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	7132	ENSG00000067182
14	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
15	ENSG00000154589	NA	LY96	lymphocyte antigen 96	23643	ENSG00000154589
16	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
17	ENSG00000172936	NA	MYD88	myeloid differentiation primary response gene (88)	4615	ENSG00000172936
18	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
19	ENSG00000114353	NA	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	2771	ENSG00000114353
20	ENSG00000136869	NA	TLR4	toll-like receptor 4	7099	ENSG00000136869

Database:KEGG pathway       Name:Natural killer cell mediated cytotoxicity       ID:04650
C=136; O=20; E=4.23; R=4.73; rawP=8.86e-09; adjP=7.37e-08
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000126264	NA	HCST	hematopoietic cell signal transducer	10870	ENSG00000126264
2	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
3	ENSG00000158869	NA	FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	2207	ENSG00000158869
4	ENSG00000159128	NA	IFNGR2	interferon gamma receptor 2 (interferon gamma transducer 1)	3460	ENSG00000159128
5	ENSG00000111679	NA	PTPN6	protein tyrosine phosphatase, non-receptor type 6	5777	ENSG00000111679
6	ENSG00000120889	NA	TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	8795	ENSG00000120889
7	ENSG00000107758	NA	PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	5532	ENSG00000107758
8	ENSG00000173535	NA	TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	8794	ENSG00000173535
9	ENSG00000043462	NA	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	3937	ENSG00000043462
10	ENSG00000162747	NA	FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	2215	ENSG00000162747
11	ENSG00000203747	NA	FCGR3A	Fc fragment of IgG, low affinity IIIa, receptor (CD16a)	2214	ENSG00000203747
12	ENSG00000026103	NA	FAS	Fas (TNF receptor superfamily, member 6)	355	ENSG00000026103
13	ENSG00000160255	NA	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	3689	ENSG00000160255
14	ENSG00000141968	NA	VAV1	vav 1 guanine nucleotide exchange factor	7409	ENSG00000141968
15	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
16	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
17	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
18	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
19	ENSG00000011600	NA	TYROBP	TYRO protein tyrosine kinase binding protein	7305	ENSG00000011600
20	ENSG00000165025	NA	SYK	spleen tyrosine kinase	6850	ENSG00000165025

Database:KEGG pathway       Name:Long-term depression       ID:04730
C=70; O=14; E=2.17; R=6.44; rawP=2.78e-08; adjP=2.21e-07
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000087460	NA	GNAS	GNAS complex locus	2778	ENSG00000087460
2	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
3	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
4	ENSG00000127472	NA	PLA2G5	phospholipase A2, group V	5322	ENSG00000127472
5	ENSG00000017427	NA	IGF1	insulin-like growth factor 1 (somatomedin C)	3479	ENSG00000017427
6	ENSG00000156052	NA	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	2776	ENSG00000156052
7	ENSG00000123104	NA	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	3709	ENSG00000123104
8	ENSG00000254087	NA	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	4067	ENSG00000254087
9	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841
10	ENSG00000120063	NA	GNA13	guanine nucleotide binding protein (G protein), alpha 13	10672	ENSG00000120063
11	ENSG00000065135	NA	GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	2773	ENSG00000065135
12	ENSG00000114353	NA	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	2771	ENSG00000114353
13	ENSG00000137713	NA	PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	5519	ENSG00000137713
14	ENSG00000188257	NA	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	5320	ENSG00000188257

Database:KEGG pathway       Name:Lysosome       ID:04142
C=121; O=18; E=3.76; R=4.79; rawP=4.04e-08; adjP=3.08e-07
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000018280	NA	SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	6556	ENSG00000018280
2	ENSG00000131238	NA	PPT1	palmitoyl-protein thioesterase 1	5538	ENSG00000131238
3	ENSG00000101160	NA	CTSZ	cathepsin Z	1522	ENSG00000101160
4	ENSG00000104774	NA	MAN2B1	mannosidase, alpha, class 2B, member 1	4125	ENSG00000104774
5	ENSG00000107798	NA	LIPA	lipase A, lysosomal acid, cholesterol esterase	3988	ENSG00000107798
6	ENSG00000141458	NA	NPC1	Niemann-Pick disease, type C1	4864	ENSG00000141458
7	ENSG00000163131	NA	CTSS	cathepsin S	1520	ENSG00000163131
8	ENSG00000109861	NA	CTSC	cathepsin C	1075	ENSG00000109861
9	ENSG00000157823	NA	AP3S2	adaptor-related protein complex 3, sigma 2 subunit	10239	ENSG00000250021 ENSG00000157823
10	ENSG00000090674	NA	MCOLN1	mucolipin 1	57192	ENSG00000090674
11	ENSG00000162511	NA	LAPTM5	lysosomal protein transmembrane 5	7805	ENSG00000162511
12	ENSG00000106367	NA	AP1S1	adaptor-related protein complex 1, sigma 1 subunit	1174	ENSG00000106367
13	ENSG00000122705	NA	CLTA	clathrin, light chain A	1211	ENSG00000122705
14	ENSG00000170266	NA	GLB1	galactosidase, beta 1	2720	ENSG00000170266
15	ENSG00000100600	NA	LGMN	legumain	5641	ENSG00000100600
16	ENSG00000188603	NA	CLN3	ceroid-lipofuscinosis, neuronal 3	1201	ENSG00000261832 ENSG00000188603
17	ENSG00000198951	NA	NAGA	N-acetylgalactosaminidase, alpha-	4668	ENSG00000198951
18	ENSG00000102575	NA	ACP5	acid phosphatase 5, tartrate resistant	54	ENSG00000102575

Database:KEGG pathway       Name:Neurotrophin signaling pathway       ID:04722
C=127; O=18; E=3.95; R=4.56; rawP=8.65e-08; adjP=6.33e-07
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
2	ENSG00000146232	NA	NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	4794	ENSG00000146232
3	ENSG00000117676	NA	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	6195	ENSG00000117676
4	ENSG00000141510	NA	TP53	tumor protein p53	7157	ENSG00000141510
5	ENSG00000127314	NA	RAP1B	RAP1B, member of RAS oncogene family	5908	ENSG00000127314
6	ENSG00000097007	NA	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	25	ENSG00000097007
7	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
8	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
9	ENSG00000163932	NA	PRKCD	protein kinase C, delta	5580	ENSG00000163932
10	ENSG00000198001	NA	IRAK4	interleukin-1 receptor-associated kinase 4	51135	ENSG00000198001
11	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
12	ENSG00000134070	NA	IRAK2	interleukin-1 receptor-associated kinase 2	3656	ENSG00000134070
13	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
14	ENSG00000141522	NA	ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	396	ENSG00000141522
15	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
16	ENSG00000164924	NA	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	7534	ENSG00000164924
17	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
18	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039

Database:KEGG pathway       Name:T cell receptor signaling pathway       ID:04660
C=108; O=16; E=3.36; R=4.77; rawP=2.40e-07; adjP=1.69e-06
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000010610	NA	CD4	CD4 molecule	920	ENSG00000010610
2	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
3	ENSG00000146232	NA	NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	4794	ENSG00000146232
4	ENSG00000111679	NA	PTPN6	protein tyrosine phosphatase, non-receptor type 6	5777	ENSG00000111679
5	ENSG00000107758	NA	PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	5532	ENSG00000107758
6	ENSG00000136634	NA	IL10	interleukin 10	3586	ENSG00000136634
7	ENSG00000043462	NA	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	3937	ENSG00000043462
8	ENSG00000081237	NA	PTPRC	protein tyrosine phosphatase, receptor type, C	5788	ENSG00000081237
9	ENSG00000141968	NA	VAV1	vav 1 guanine nucleotide exchange factor	7409	ENSG00000141968
10	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
11	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
12	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
13	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
14	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
15	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
16	ENSG00000178562	NA	CD28	CD28 molecule	940	ENSG00000178562

Database:KEGG pathway       Name:MAPK signaling pathway       ID:04010
C=268; O=26; E=8.33; R=3.12; rawP=3.62e-07; adjP=2.45e-06
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
2	ENSG00000117676	NA	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	6195	ENSG00000117676
3	ENSG00000127472	NA	PLA2G5	phospholipase A2, group V	5322	ENSG00000127472
4	ENSG00000141510	NA	TP53	tumor protein p53	7157	ENSG00000141510
5	ENSG00000127314	NA	RAP1B	RAP1B, member of RAS oncogene family	5908	ENSG00000127314
6	ENSG00000106799	NA	TGFBR1	transforming growth factor, beta receptor 1	7046	ENSG00000106799
7	ENSG00000170458	NA	CD14	CD14 molecule	929	ENSG00000170458
8	ENSG00000107758	NA	PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	5532	ENSG00000107758
9	ENSG00000134853	NA	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	5156	ENSG00000134853
10	ENSG00000026103	NA	FAS	Fas (TNF receptor superfamily, member 6)	355	ENSG00000026103
11	ENSG00000188257	NA	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	5320	ENSG00000188257
12	ENSG00000115594	NA	IL1R1	interleukin 1 receptor, type I	3554	ENSG00000115594
13	ENSG00000204209	NA	DAXX	death-domain associated protein	1616	ENSG00000204209
14	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
15	ENSG00000171777	NA	RASGRP4	RAS guanyl releasing protein 4	115727	ENSG00000171777
16	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
17	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
18	ENSG00000067182	NA	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	7132	ENSG00000067182
19	ENSG00000173327	NA	MAP3K11	mitogen-activated protein kinase kinase kinase 11	4296	ENSG00000173327
20	ENSG00000115590	NA	IL1R2	interleukin 1 receptor, type II	7850	ENSG00000115590
21	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
22	ENSG00000011485	NA	PPP5C	protein phosphatase 5, catalytic subunit	5536	ENSG00000011485
23	ENSG00000141480	NA	ARRB2	arrestin, beta 2	409	ENSG00000141480
24	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
25	ENSG00000113721	NA	PDGFRB	platelet-derived growth factor receptor, beta polypeptide	5159	ENSG00000113721
26	ENSG00000101109	NA	STK4	serine/threonine kinase 4	6789	ENSG00000101109

Database:KEGG pathway       Name:Pancreatic secretion       ID:04972
C=101; O=15; E=3.14; R=4.78; rawP=5.48e-07; adjP=3.58e-06
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000087460	NA	GNAS	GNAS complex locus	2778	ENSG00000087460
2	ENSG00000167461	NA	RAB8A	RAB8A, member RAS oncogene family	4218	ENSG00000167461
3	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
4	ENSG00000163751	NA	CPA3	carboxypeptidase A3 (mast cell)	1359	ENSG00000163751
5	ENSG00000127472	NA	PLA2G5	phospholipase A2, group V	5322	ENSG00000127472
6	ENSG00000105514	NA	RAB3D	RAB3D, member RAS oncogene family	9545	ENSG00000105514
7	ENSG00000127314	NA	RAP1B	RAP1B, member of RAS oncogene family	5908	ENSG00000127314
8	ENSG00000138031	NA	ADCY3	adenylate cyclase 3	109	ENSG00000138031
9	ENSG00000156052	NA	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	2776	ENSG00000156052
10	ENSG00000069849	NA	ATP1B3	ATPase, Na+/K+ transporting, beta 3 polypeptide	483	ENSG00000069849
11	ENSG00000123104	NA	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	3709	ENSG00000123104
12	ENSG00000041353	NA	RAB27B	RAB27B, member RAS oncogene family	5874	ENSG00000041353
13	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841
14	ENSG00000188257	NA	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	5320	ENSG00000188257
15	ENSG00000105409	NA	ATP1A3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	478	ENSG00000105409

Database:KEGG pathway       Name:Gap junction       ID:04540
C=90; O=14; E=2.80; R=5.01; rawP=7.30e-07; adjP=4.61e-06
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000087460	NA	GNAS	GNAS complex locus	2778	ENSG00000087460
2	ENSG00000198121	NA	LPAR1	lysophosphatidic acid receptor 1	1902	ENSG00000198121
3	ENSG00000137267	NA	TUBB2A	tubulin, beta 2A class IIa	7280	ENSG00000137267
4	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
5	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
6	ENSG00000138031	NA	ADCY3	adenylate cyclase 3	109	ENSG00000138031
7	ENSG00000156052	NA	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	2776	ENSG00000156052
8	ENSG00000123104	NA	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	3709	ENSG00000123104
9	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841
10	ENSG00000065135	NA	GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	2773	ENSG00000065135
11	ENSG00000114353	NA	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	2771	ENSG00000114353
12	ENSG00000134853	NA	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	5156	ENSG00000134853
13	ENSG00000197122	NA	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	6714	ENSG00000197122
14	ENSG00000113721	NA	PDGFRB	platelet-derived growth factor receptor, beta polypeptide	5159	ENSG00000113721

Database:KEGG pathway       Name:Rheumatoid arthritis       ID:05323
C=91; O=14; E=2.83; R=4.95; rawP=8.39e-07; adjP=5.12e-06
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000160255	NA	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	3689	ENSG00000160255
2	ENSG00000161955	NA	TNFSF13	tumor necrosis factor (ligand) superfamily, member 13	8741	ENSG00000161955
3	ENSG00000114013	NA	CD86	CD86 molecule	942	ENSG00000114013
4	ENSG00000184371	NA	CSF1	colony stimulating factor 1 (macrophage)	1435	ENSG00000184371
5	ENSG00000227507	NA	LTB	lymphotoxin beta (TNF superfamily, member 3)	4050	ENSG00000227507
6	ENSG00000102524	NA	TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b	10673	ENSG00000102524
7	ENSG00000124875	NA	CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	6372	ENSG00000124875
8	ENSG00000196611	NA	MMP1	matrix metallopeptidase 1 (interstitial collagenase)	4312	ENSG00000196611
9	ENSG00000150782	NA	IL18	interleukin 18 (interferon-gamma-inducing factor)	3606	ENSG00000150782
10	ENSG00000110944	NA	IL23A	interleukin 23, alpha subunit p19	51561	ENSG00000110944
11	ENSG00000136869	NA	TLR4	toll-like receptor 4	7099	ENSG00000136869
12	ENSG00000141655	NA	TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	8792	ENSG00000141655
13	ENSG00000178562	NA	CD28	CD28 molecule	940	ENSG00000178562
14	ENSG00000102575	NA	ACP5	acid phosphatase 5, tartrate resistant	54	ENSG00000102575

Database:KEGG pathway       Name:Cell adhesion molecules (CAMs)       ID:04514
C=133; O=17; E=4.13; R=4.11; rawP=8.77e-07; adjP=5.18e-06
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000002586	NA	CD99	CD99 molecule	4267	ENSG00000002586
2	ENSG00000160255	NA	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	3689	ENSG00000160255
3	ENSG00000081237	NA	PTPRC	protein tyrosine phosphatase, receptor type, C	5788	ENSG00000081237
4	ENSG00000010610	NA	CD4	CD4 molecule	920	ENSG00000010610
5	ENSG00000130202	NA	PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	5819	ENSG00000130202
6	ENSG00000114013	NA	CD86	CD86 molecule	942	ENSG00000114013
7	ENSG00000110876	NA	SELPLG	selectin P ligand	6404	ENSG00000110876
8	ENSG00000115232	NA	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	3676	ENSG00000115232
9	ENSG00000177707	NA	PVRL3	poliovirus receptor-related 3	25945	ENSG00000177707
10	ENSG00000169896	NA	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	3684	ENSG00000169896
11	ENSG00000162706	NA	CADM3	cell adhesion molecule 3	57863	ENSG00000162706
12	ENSG00000188404	NA	SELL	selectin L	6402	ENSG00000188404
13	ENSG00000162692	NA	VCAM1	vascular cell adhesion molecule 1	7412	ENSG00000162692
14	ENSG00000158769	NA	F11R	F11 receptor	50848	ENSG00000158769
15	ENSG00000160223	NA	ICOSLG	inducible T-cell co-stimulator ligand	23308	ENSG00000160223
16	ENSG00000088827	NA	SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	6614	ENSG00000088827
17	ENSG00000178562	NA	CD28	CD28 molecule	940	ENSG00000178562

Database:KEGG pathway       Name:Acute myeloid leukemia       ID:05221
C=57; O=11; E=1.77; R=6.21; rawP=1.24e-06; adjP=7.09e-06
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000112033	NA	PPARD	peroxisome proliferator-activated receptor delta	5467	ENSG00000112033
2	ENSG00000131759	NA	RARA	retinoic acid receptor, alpha	5914	ENSG00000131759
3	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
4	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
5	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
6	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
7	ENSG00000126561	NA	STAT5A	signal transducer and activator of transcription 5A	6776	ENSG00000126561
8	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
9	ENSG00000102096	NA	PIM2	pim-2 oncogene	11040	ENSG00000102096
10	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
11	ENSG00000066336	NA	SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	6688	ENSG00000066336

Database:KEGG pathway       Name:NOD-like receptor signaling pathway       ID:04621
C=58; O=11; E=1.80; R=6.10; rawP=1.49e-06; adjP=8.26e-06
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000132357	NA	CARD6	caspase recruitment domain family, member 6	84674	ENSG00000132357
2	ENSG00000162711	NA	NLRP3	NLR family, pyrin domain containing 3	114548	ENSG00000162711
3	ENSG00000187796	NA	CARD9	caspase recruitment domain family, member 9	64170	ENSG00000187796
4	ENSG00000103490	NA	PYCARD	PYD and CARD domain containing	29108	ENSG00000103490
5	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
6	ENSG00000167207	NA	NOD2	nucleotide-binding oligomerization domain containing 2	64127	ENSG00000167207
7	ENSG00000150782	NA	IL18	interleukin 18 (interferon-gamma-inducing factor)	3606	ENSG00000150782
8	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
9	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
10	ENSG00000103313	NA	MEFV	Mediterranean fever	4210	ENSG00000103313
11	ENSG00000140368	NA	PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	9051	ENSG00000140368

Database:KEGG pathway       Name:Arachidonic acid metabolism       ID:00590
C=59; O=11; E=1.83; R=6.00; rawP=1.78e-06; adjP=9.58e-06
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000012779	NA	ALOX5	arachidonate 5-lipoxygenase	240	ENSG00000012779
2	ENSG00000124212	NA	PTGIS	prostaglandin I2 (prostacyclin) synthase	5740	ENSG00000124212
3	ENSG00000127472	NA	PLA2G5	phospholipase A2, group V	5322	ENSG00000127472
4	ENSG00000059377	NA	TBXAS1	thromboxane A synthase 1 (platelet)	6916	ENSG00000059377
5	ENSG00000095303	NA	PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	5742	ENSG00000095303
6	ENSG00000131067	NA	GGT7	gamma-glutamyltransferase 7	2686	ENSG00000131067
7	ENSG00000163803	NA	PLB1	phospholipase B1	151056	ENSG00000163803
8	ENSG00000148344	NA	PTGES	prostaglandin E synthase	9536	ENSG00000148344
9	ENSG00000186529	NA	CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	4051	ENSG00000186529
10	ENSG00000163106	NA	HPGDS	hematopoietic prostaglandin D synthase	27306	ENSG00000163106
11	ENSG00000188257	NA	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	5320	ENSG00000188257

Database:KEGG pathway       Name:Shigellosis       ID:05131
C=61; O=11; E=1.90; R=5.80; rawP=2.51e-06; adjP=1.31e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000097007	NA	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	25	ENSG00000097007
2	ENSG00000015285	NA	WAS	Wiskott-Aldrich syndrome	7454	ENSG00000015285
3	ENSG00000112290	NA	WASF1	WAS protein family, member 1	8936	ENSG00000112290
4	ENSG00000180353	NA	HCLS1	hematopoietic cell-specific Lyn substrate 1	3059	ENSG00000180353
5	ENSG00000130429	NA	ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	10095	ENSG00000130429
6	ENSG00000162704	NA	ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	10092	ENSG00000162704
7	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
8	ENSG00000167207	NA	NOD2	nucleotide-binding oligomerization domain containing 2	64127	ENSG00000167207
9	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
10	ENSG00000026508	NA	CD44	CD44 molecule (Indian blood group)	960	ENSG00000026508
11	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039

Database:KEGG pathway       Name:Gastric acid secretion       ID:04971
C=74; O=12; E=2.30; R=5.22; rawP=2.86e-06; adjP=1.45e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000087460	NA	GNAS	GNAS complex locus	2778	ENSG00000087460
2	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
3	ENSG00000157551	NA	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15	3772	ENSG00000157551
4	ENSG00000138031	NA	ADCY3	adenylate cyclase 3	109	ENSG00000138031
5	ENSG00000156052	NA	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	2776	ENSG00000156052
6	ENSG00000069849	NA	ATP1B3	ATPase, Na+/K+ transporting, beta 3 polypeptide	483	ENSG00000069849
7	ENSG00000123104	NA	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	3709	ENSG00000123104
8	ENSG00000180616	NA	SSTR2	somatostatin receptor 2	6752	ENSG00000180616
9	ENSG00000065135	NA	GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	2773	ENSG00000065135
10	ENSG00000114353	NA	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	2771	ENSG00000114353
11	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841
12	ENSG00000105409	NA	ATP1A3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	478	ENSG00000105409

Database:KEGG pathway       Name:Regulation of actin cytoskeleton       ID:04810
C=213; O=21; E=6.62; R=3.17; rawP=3.62e-06; adjP=1.79e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
2	ENSG00000112290	NA	WASF1	WAS protein family, member 1	8936	ENSG00000112290
3	ENSG00000115232	NA	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	3676	ENSG00000115232
4	ENSG00000140575	NA	IQGAP1	IQ motif containing GTPase activating protein 1	8826	ENSG00000140575
5	ENSG00000169896	NA	ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	3684	ENSG00000169896
6	ENSG00000170458	NA	CD14	CD14 molecule	929	ENSG00000170458
7	ENSG00000134853	NA	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	5156	ENSG00000134853
8	ENSG00000005961	NA	ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	3674	ENSG00000005961
9	ENSG00000160255	NA	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	3689	ENSG00000160255
10	ENSG00000141968	NA	VAV1	vav 1 guanine nucleotide exchange factor	7409	ENSG00000141968
11	ENSG00000015285	NA	WAS	Wiskott-Aldrich syndrome	7454	ENSG00000015285
12	ENSG00000130429	NA	ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	10095	ENSG00000130429
13	ENSG00000123338	NA	NCKAP1L	NCK-associated protein 1-like	3071	ENSG00000123338
14	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
15	ENSG00000162704	NA	ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	10092	ENSG00000162704
16	ENSG00000164171	NA	ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	3673	ENSG00000164171
17	ENSG00000127084	NA	FGD3	FYVE, RhoGEF and PH domain containing 3	89846	ENSG00000127084
18	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
19	ENSG00000140678	NA	ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)	3687	ENSG00000140678
20	ENSG00000120063	NA	GNA13	guanine nucleotide binding protein (G protein), alpha 13	10672	ENSG00000120063
21	ENSG00000113721	NA	PDGFRB	platelet-derived growth factor receptor, beta polypeptide	5159	ENSG00000113721

Database:KEGG pathway       Name:VEGF signaling pathway       ID:04370
C=76; O=12; E=2.36; R=5.08; rawP=3.82e-06; adjP=1.84e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
2	ENSG00000027869	NA	SH2D2A	SH2 domain containing 2A	9047	ENSG00000027869
3	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
4	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
5	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
6	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
7	ENSG00000127472	NA	PLA2G5	phospholipase A2, group V	5322	ENSG00000127472
8	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
9	ENSG00000107758	NA	PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	5532	ENSG00000107758
10	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
11	ENSG00000197122	NA	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	6714	ENSG00000197122
12	ENSG00000188257	NA	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	5320	ENSG00000188257

Database:KEGG pathway       Name:Glioma       ID:05214
C=65; O=11; E=2.02; R=5.45; rawP=4.81e-06; adjP=2.26e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
2	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
3	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
4	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
5	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
6	ENSG00000141510	NA	TP53	tumor protein p53	7157	ENSG00000141510
7	ENSG00000017427	NA	IGF1	insulin-like growth factor 1 (somatomedin C)	3479	ENSG00000017427
8	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
9	ENSG00000124762	NA	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	1026	ENSG00000124762
10	ENSG00000134853	NA	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	5156	ENSG00000134853
11	ENSG00000113721	NA	PDGFRB	platelet-derived growth factor receptor, beta polypeptide	5159	ENSG00000113721

Database:KEGG pathway       Name:p53 signaling pathway       ID:04115
C=68; O=11; E=2.11; R=5.21; rawP=7.56e-06; adjP=3.46e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000130766	NA	SESN2	sestrin 2	83667	ENSG00000130766
2	ENSG00000120889	NA	TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	8795	ENSG00000120889
3	ENSG00000141510	NA	TP53	tumor protein p53	7157	ENSG00000141510
4	ENSG00000017427	NA	IGF1	insulin-like growth factor 1 (somatomedin C)	3479	ENSG00000017427
5	ENSG00000106366	NA	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	5054	ENSG00000106366
6	ENSG00000183765	NA	CHEK2	checkpoint kinase 2	11200	ENSG00000183765
7	ENSG00000120868	NA	APAF1	apoptotic peptidase activating factor 1	317	ENSG00000120868
8	ENSG00000124762	NA	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	1026	ENSG00000124762
9	ENSG00000118971	NA	CCND2	cyclin D2	894	ENSG00000118971
10	ENSG00000137801	NA	THBS1	thrombospondin 1	7057	ENSG00000137801
11	ENSG00000026103	NA	FAS	Fas (TNF receptor superfamily, member 6)	355	ENSG00000026103

Database:KEGG pathway       Name:Pathogenic Escherichia coli infection       ID:05130
C=56; O=10; E=1.74; R=5.75; rawP=7.87e-06; adjP=3.51e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000097007	NA	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	25	ENSG00000097007
2	ENSG00000137267	NA	TUBB2A	tubulin, beta 2A class IIa	7280	ENSG00000137267
3	ENSG00000015285	NA	WAS	Wiskott-Aldrich syndrome	7454	ENSG00000015285
4	ENSG00000180353	NA	HCLS1	hematopoietic cell-specific Lyn substrate 1	3059	ENSG00000180353
5	ENSG00000130429	NA	ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	10095	ENSG00000130429
6	ENSG00000162704	NA	ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	10092	ENSG00000162704
7	ENSG00000164924	NA	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	7534	ENSG00000164924
8	ENSG00000154589	NA	LY96	lymphocyte antigen 96	23643	ENSG00000154589
9	ENSG00000170458	NA	CD14	CD14 molecule	929	ENSG00000170458
10	ENSG00000136869	NA	TLR4	toll-like receptor 4	7099	ENSG00000136869

Database:KEGG pathway       Name:African trypanosomiasis       ID:05143
C=35; O=8; E=1.09; R=7.36; rawP=9.48e-06; adjP=4.13e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
2	ENSG00000150782	NA	IL18	interleukin 18 (interferon-gamma-inducing factor)	3606	ENSG00000150782
3	ENSG00000156052	NA	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	2776	ENSG00000156052
4	ENSG00000162692	NA	VCAM1	vascular cell adhesion molecule 1	7412	ENSG00000162692
5	ENSG00000136634	NA	IL10	interleukin 10	3586	ENSG00000136634
6	ENSG00000172936	NA	MYD88	myeloid differentiation primary response gene (88)	4615	ENSG00000172936
7	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841
8	ENSG00000026103	NA	FAS	Fas (TNF receptor superfamily, member 6)	355	ENSG00000026103

Database:KEGG pathway       Name:Chronic myeloid leukemia       ID:05220
C=73; O=11; E=2.27; R=4.85; rawP=1.52e-05; adjP=6.13e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000097007	NA	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	25	ENSG00000097007
2	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
3	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
4	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
5	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
6	ENSG00000141510	NA	TP53	tumor protein p53	7157	ENSG00000141510
7	ENSG00000106799	NA	TGFBR1	transforming growth factor, beta receptor 1	7046	ENSG00000106799
8	ENSG00000126561	NA	STAT5A	signal transducer and activator of transcription 5A	6776	ENSG00000126561
9	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
10	ENSG00000124762	NA	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	1026	ENSG00000124762
11	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039

Database:KEGG pathway       Name:Amino sugar and nucleotide sugar metabolism       ID:00520
C=48; O=9; E=1.49; R=6.03; rawP=1.48e-05; adjP=6.13e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000111726	NA	CMAS	cytidine monophosphate N-acetylneuraminic acid synthetase	55907	ENSG00000111726
2	ENSG00000131459	NA	GFPT2	glutamine-fructose-6-phosphate transaminase 2	9945	ENSG00000131459
3	ENSG00000178802	NA	MPI	mannose phosphate isomerase	4351	ENSG00000178802
4	ENSG00000117143	NA	UAP1	UDP-N-acteylglucosamine pyrophosphorylase 1	6675	ENSG00000117143
5	ENSG00000109814	NA	UGDH	UDP-glucose 6-dehydrogenase	7358	ENSG00000109814
6	ENSG00000135838	NA	NPL	N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)	80896	ENSG00000135838
7	ENSG00000140650	NA	PMM2	phosphomannomutase 2	5373	ENSG00000140650
8	ENSG00000160883	NA	HK3	hexokinase 3 (white cell)	3101	ENSG00000160883
9	ENSG00000133048	NA	CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	1116	ENSG00000133048

Database:KEGG pathway       Name:Intestinal immune network for IgA production       ID:04672
C=48; O=9; E=1.49; R=6.03; rawP=1.48e-05; adjP=6.13e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000111321	NA	LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)	4055	ENSG00000111321
2	ENSG00000161955	NA	TNFSF13	tumor necrosis factor (ligand) superfamily, member 13	8741	ENSG00000161955
3	ENSG00000134470	NA	IL15RA	interleukin 15 receptor, alpha	3601	ENSG00000134470
4	ENSG00000114013	NA	CD86	CD86 molecule	942	ENSG00000114013
5	ENSG00000115232	NA	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	3676	ENSG00000115232
6	ENSG00000102524	NA	TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b	10673	ENSG00000102524
7	ENSG00000136634	NA	IL10	interleukin 10	3586	ENSG00000136634
8	ENSG00000160223	NA	ICOSLG	inducible T-cell co-stimulator ligand	23308	ENSG00000160223
9	ENSG00000178562	NA	CD28	CD28 molecule	940	ENSG00000178562

Database:KEGG pathway       Name:GnRH signaling pathway       ID:04912
C=101; O=13; E=3.14; R=4.14; rawP=1.54e-05; adjP=6.13e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000087460	NA	GNAS	GNAS complex locus	2778	ENSG00000087460
2	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
3	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
4	ENSG00000163932	NA	PRKCD	protein kinase C, delta	5580	ENSG00000163932
5	ENSG00000127472	NA	PLA2G5	phospholipase A2, group V	5322	ENSG00000127472
6	ENSG00000157227	NA	MMP14	matrix metallopeptidase 14 (membrane-inserted)	4323	ENSG00000157227
7	ENSG00000138031	NA	ADCY3	adenylate cyclase 3	109	ENSG00000138031
8	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
9	ENSG00000156052	NA	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	2776	ENSG00000156052
10	ENSG00000123104	NA	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	3709	ENSG00000123104
11	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841
12	ENSG00000197122	NA	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	6714	ENSG00000197122
13	ENSG00000188257	NA	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	5320	ENSG00000188257

Database:KEGG pathway       Name:ErbB signaling pathway       ID:04012
C=87; O=12; E=2.70; R=4.44; rawP=1.60e-05; adjP=6.23e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000143322	NA	ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	27	ENSG00000143322
2	ENSG00000097007	NA	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	25	ENSG00000097007
3	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
4	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
5	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
6	ENSG00000109321	NA	AREG	amphiregulin	374	ENSG00000109321
7	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
8	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
9	ENSG00000126561	NA	STAT5A	signal transducer and activator of transcription 5A	6776	ENSG00000126561
10	ENSG00000124762	NA	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	1026	ENSG00000124762
11	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
12	ENSG00000197122	NA	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	6714	ENSG00000197122

Database:KEGG pathway       Name:Focal adhesion       ID:04510
C=200; O=19; E=6.21; R=3.06; rawP=1.75e-05; adjP=6.67e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000135862	NA	LAMC1	laminin, gamma 1 (formerly LAMB2)	3915	ENSG00000135862
2	ENSG00000115232	NA	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	3676	ENSG00000115232
3	ENSG00000081052	NA	COL4A4	collagen, type IV, alpha 4	1286	ENSG00000081052
4	ENSG00000127314	NA	RAP1B	RAP1B, member of RAS oncogene family	5908	ENSG00000127314
5	ENSG00000134853	NA	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	5156	ENSG00000134853
6	ENSG00000197122	NA	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	6714	ENSG00000197122
7	ENSG00000005961	NA	ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	3674	ENSG00000005961
8	ENSG00000163359	NA	COL6A3	collagen, type VI, alpha 3	1293	ENSG00000163359
9	ENSG00000137801	NA	THBS1	thrombospondin 1	7057	ENSG00000137801
10	ENSG00000141968	NA	VAV1	vav 1 guanine nucleotide exchange factor	7409	ENSG00000141968
11	ENSG00000118785	NA	SPP1	secreted phosphoprotein 1	6696	ENSG00000118785
12	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
13	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
14	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
15	ENSG00000164171	NA	ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	3673	ENSG00000164171
16	ENSG00000017427	NA	IGF1	insulin-like growth factor 1 (somatomedin C)	3479	ENSG00000017427
17	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
18	ENSG00000118971	NA	CCND2	cyclin D2	894	ENSG00000118971
19	ENSG00000113721	NA	PDGFRB	platelet-derived growth factor receptor, beta polypeptide	5159	ENSG00000113721

Database:KEGG pathway       Name:Endocytosis       ID:04144
C=201; O=19; E=6.25; R=3.04; rawP=1.88e-05; adjP=7.02e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000125388	NA	GRK4	G protein-coupled receptor kinase 4	2868	ENSG00000125388
2	ENSG00000047365	NA	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	116984	ENSG00000047365
3	ENSG00000161203	NA	AP2M1	adaptor-related protein complex 2, mu 1 subunit	1173	ENSG00000161203
4	ENSG00000125637	NA	PSD4	pleckstrin and Sec7 domain containing 4	23550	ENSG00000125637
5	ENSG00000180871	NA	CXCR2	chemokine (C-X-C motif) receptor 2	3579	ENSG00000180871
6	ENSG00000165457	NA	FOLR2	folate receptor 2 (fetal)	2350	ENSG00000165457
7	ENSG00000106799	NA	TGFBR1	transforming growth factor, beta receptor 1	7046	ENSG00000106799
8	ENSG00000134853	NA	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	5156	ENSG00000134853
9	ENSG00000197122	NA	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	6714	ENSG00000197122
10	ENSG00000084070	NA	SMAP2	small ArfGAP2	64744	ENSG00000084070
11	ENSG00000114331	NA	ACAP2	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2	23527	ENSG00000114331
12	ENSG00000153071	NA	DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	1601	ENSG00000153071
13	ENSG00000122705	NA	CLTA	clathrin, light chain A	1211	ENSG00000122705
14	ENSG00000134460	NA	IL2RA	interleukin 2 receptor, alpha	3559	ENSG00000134460
15	ENSG00000165527	NA	ARF6	ADP-ribosylation factor 6	382	ENSG00000165527
16	ENSG00000141480	NA	ARRB2	arrestin, beta 2	409	ENSG00000141480
17	ENSG00000163464	NA	CXCR1	chemokine (C-X-C motif) receptor 1	3577	ENSG00000163464
18	ENSG00000108774	NA	RAB5C	RAB5C, member RAS oncogene family	5878	ENSG00000108774
19	ENSG00000182578	NA	CSF1R	colony stimulating factor 1 receptor	1436	ENSG00000182578

Database:KEGG pathway       Name:Malaria       ID:05144
C=51; O=9; E=1.58; R=5.68; rawP=2.47e-05; adjP=9.04e-05
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000160255	NA	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	3689	ENSG00000160255
2	ENSG00000203710	NA	CR1	complement component (3b/4b) receptor 1 (Knops blood group)	1378	ENSG00000203710
3	ENSG00000123384	NA	LRP1	low density lipoprotein receptor-related protein 1	4035	ENSG00000123384
4	ENSG00000150782	NA	IL18	interleukin 18 (interferon-gamma-inducing factor)	3606	ENSG00000150782
5	ENSG00000162692	NA	VCAM1	vascular cell adhesion molecule 1	7412	ENSG00000162692
6	ENSG00000136634	NA	IL10	interleukin 10	3586	ENSG00000136634
7	ENSG00000172936	NA	MYD88	myeloid differentiation primary response gene (88)	4615	ENSG00000172936
8	ENSG00000136869	NA	TLR4	toll-like receptor 4	7099	ENSG00000136869
9	ENSG00000137801	NA	THBS1	thrombospondin 1	7057	ENSG00000137801

Database:KEGG pathway       Name:Non-small cell lung cancer       ID:05223
C=54; O=9; E=1.68; R=5.36; rawP=3.97e-05; adjP=0.0001
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
2	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
3	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
4	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
5	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
6	ENSG00000141510	NA	TP53	tumor protein p53	7157	ENSG00000141510
7	ENSG00000136653	NA	RASSF5	Ras association (RalGDS/AF-6) domain family member 5	83593	ENSG00000136653
8	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
9	ENSG00000101109	NA	STK4	serine/threonine kinase 4	6789	ENSG00000101109

Database:KEGG pathway       Name:Aldosterone-regulated sodium reabsorption       ID:04960
C=42; O=8; E=1.30; R=6.13; rawP=3.92e-05; adjP=0.0001
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
2	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
3	ENSG00000117594	NA	HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	3290	ENSG00000117594
4	ENSG00000017427	NA	IGF1	insulin-like growth factor 1 (somatomedin C)	3479	ENSG00000017427
5	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
6	ENSG00000069849	NA	ATP1B3	ATPase, Na+/K+ transporting, beta 3 polypeptide	483	ENSG00000069849
7	ENSG00000065054	NA	SLC9A3R2	solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2	9351	ENSG00000065054
8	ENSG00000105409	NA	ATP1A3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	478	ENSG00000105409

Database:KEGG pathway       Name:Calcium signaling pathway       ID:04020
C=177; O=17; E=5.50; R=3.09; rawP=4.15e-05; adjP=0.0001
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000135124	NA	P2RX4	purinergic receptor P2X, ligand-gated ion channel, 4	5025	ENSG00000135124
2	ENSG00000122420	NA	PTGFR	prostaglandin F receptor (FP)	5737	ENSG00000122420
3	ENSG00000169403	NA	PTAFR	platelet-activating factor receptor	5724	ENSG00000169403
4	ENSG00000060558	NA	GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	2769	ENSG00000060558
5	ENSG00000154678	NA	PDE1C	phosphodiesterase 1C, calmodulin-dependent 70kDa	5137	ENSG00000154678
6	ENSG00000107758	NA	PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	5532	ENSG00000107758
7	ENSG00000123104	NA	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	3709	ENSG00000123104
8	ENSG00000134853	NA	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	5156	ENSG00000134853
9	ENSG00000087460	NA	GNAS	GNAS complex locus	2778	ENSG00000087460
10	ENSG00000115353	NA	TACR1	tachykinin receptor 1	6869	ENSG00000115353
11	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
12	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
13	ENSG00000138031	NA	ADCY3	adenylate cyclase 3	109	ENSG00000138031
14	ENSG00000156052	NA	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	2776	ENSG00000156052
15	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841
16	ENSG00000113721	NA	PDGFRB	platelet-derived growth factor receptor, beta polypeptide	5159	ENSG00000113721
17	ENSG00000196639	NA	HRH1	histamine receptor H1	3269	ENSG00000196639

Database:KEGG pathway       Name:Small cell lung cancer       ID:05222
C=85; O=11; E=2.64; R=4.17; rawP=6.51e-05; adjP=0.0002
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000135862	NA	LAMC1	laminin, gamma 1 (formerly LAMB2)	3915	ENSG00000135862
2	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
3	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
4	ENSG00000081052	NA	COL4A4	collagen, type IV, alpha 4	1286	ENSG00000081052
5	ENSG00000164171	NA	ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	3673	ENSG00000164171
6	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
7	ENSG00000141510	NA	TP53	tumor protein p53	7157	ENSG00000141510
8	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
9	ENSG00000120868	NA	APAF1	apoptotic peptidase activating factor 1	317	ENSG00000120868
10	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
11	ENSG00000005961	NA	ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	3674	ENSG00000005961

Database:KEGG pathway       Name:Carbohydrate digestion and absorption       ID:04973
C=44; O=8; E=1.37; R=5.85; rawP=5.57e-05; adjP=0.0002
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
2	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
3	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
4	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
5	ENSG00000069849	NA	ATP1B3	ATPase, Na+/K+ transporting, beta 3 polypeptide	483	ENSG00000069849
6	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841
7	ENSG00000160883	NA	HK3	hexokinase 3 (white cell)	3101	ENSG00000160883
8	ENSG00000105409	NA	ATP1A3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	478	ENSG00000105409

Database:KEGG pathway       Name:Adipocytokine signaling pathway       ID:04920
C=68; O=10; E=2.11; R=4.73; rawP=4.59e-05; adjP=0.0002
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000197142	NA	ACSL5	acyl-CoA synthetase long-chain family member 5	51703	ENSG00000197142
2	ENSG00000028137	NA	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	7133	ENSG00000028137
3	ENSG00000181856	NA	SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	6517	ENSG00000181856
4	ENSG00000106617	NA	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	51422	ENSG00000106617
5	ENSG00000146232	NA	NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	4794	ENSG00000146232
6	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
7	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
8	ENSG00000067182	NA	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	7132	ENSG00000067182
9	ENSG00000100889	NA	PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	5106	ENSG00000100889
10	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039

Database:KEGG pathway       Name:Ether lipid metabolism       ID:00565
C=36; O=7; E=1.12; R=6.26; rawP=0.0001; adjP=0.0003
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000079462	NA	PAFAH1B3	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)	5050	ENSG00000079462
2	ENSG00000146070	NA	PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	7941	ENSG00000146070
3	ENSG00000163803	NA	PLB1	phospholipase B1	151056	ENSG00000163803
4	ENSG00000153395	NA	LPCAT1	lysophosphatidylcholine acyltransferase 1	79888	ENSG00000153395
5	ENSG00000087253	NA	LPCAT2	lysophosphatidylcholine acyltransferase 2	54947	ENSG00000087253
6	ENSG00000127472	NA	PLA2G5	phospholipase A2, group V	5322	ENSG00000127472
7	ENSG00000188257	NA	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	5320	ENSG00000188257

Database:KEGG pathway       Name:Prostate cancer       ID:05215
C=89; O=11; E=2.77; R=3.98; rawP=9.95e-05; adjP=0.0003
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
2	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
3	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
4	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
5	ENSG00000141510	NA	TP53	tumor protein p53	7157	ENSG00000141510
6	ENSG00000017427	NA	IGF1	insulin-like growth factor 1 (somatomedin C)	3479	ENSG00000017427
7	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
8	ENSG00000124762	NA	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	1026	ENSG00000124762
9	ENSG00000134853	NA	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	5156	ENSG00000134853
10	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
11	ENSG00000113721	NA	PDGFRB	platelet-derived growth factor receptor, beta polypeptide	5159	ENSG00000113721

Database:KEGG pathway       Name:Neuroactive ligand-receptor interaction       ID:04080
C=272; O=21; E=8.45; R=2.48; rawP=0.0001; adjP=0.0003
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000135124	NA	P2RX4	purinergic receptor P2X, ligand-gated ion channel, 4	5025	ENSG00000135124
2	ENSG00000122420	NA	PTGFR	prostaglandin F receptor (FP)	5737	ENSG00000122420
3	ENSG00000169403	NA	PTAFR	platelet-activating factor receptor	5724	ENSG00000169403
4	ENSG00000064547	NA	LPAR2	lysophosphatidic acid receptor 2	9170	ENSG00000064547
5	ENSG00000126351	NA	THRA	thyroid hormone receptor, alpha	7067	ENSG00000126351
6	ENSG00000109738	NA	GLRB	glycine receptor, beta	2743	ENSG00000109738
7	ENSG00000171051	NA	FPR1	formyl peptide receptor 1	2357	ENSG00000171051
8	ENSG00000197405	NA	C5AR1	complement component 5a receptor 1	728	ENSG00000197405
9	ENSG00000125910	NA	S1PR4	sphingosine-1-phosphate receptor 4	8698	ENSG00000125910
10	ENSG00000125384	NA	PTGER2	prostaglandin E receptor 2 (subtype EP2), 53kDa	5732	ENSG00000125384
11	ENSG00000198121	NA	LPAR1	lysophosphatidic acid receptor 1	1902	ENSG00000198121
12	ENSG00000115353	NA	TACR1	tachykinin receptor 1	6869	ENSG00000115353
13	ENSG00000171631	NA	P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6	5031	ENSG00000171631
14	ENSG00000181631	NA	P2RY13	purinergic receptor P2Y, G-protein coupled, 13	53829	ENSG00000181631
15	ENSG00000187474	NA	FPR3	formyl peptide receptor 3	2359	ENSG00000187474
16	ENSG00000180616	NA	SSTR2	somatostatin receptor 2	6752	ENSG00000180616
17	ENSG00000121933	NA	ADORA3	adenosine A3 receptor	140	ENSG00000121933
18	ENSG00000196639	NA	HRH1	histamine receptor H1	3269	ENSG00000196639
19	ENSG00000150594	NA	ADRA2A	adrenoceptor alpha 2A	150	ENSG00000150594
20	ENSG00000171049	NA	FPR2	formyl peptide receptor 2	2358	ENSG00000171049
21	ENSG00000171860	NA	C3AR1	complement component 3a receptor 1	719	ENSG00000171860

Database:KEGG pathway       Name:Salivary secretion       ID:04970
C=89; O=11; E=2.77; R=3.98; rawP=9.95e-05; adjP=0.0003
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000087460	NA	GNAS	GNAS complex locus	2778	ENSG00000087460
2	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
3	ENSG00000104783	NA	KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	3783	ENSG00000104783
4	ENSG00000090382	NA	LYZ	lysozyme	4069	ENSG00000090382
5	ENSG00000138031	NA	ADCY3	adenylate cyclase 3	109	ENSG00000138031
6	ENSG00000156052	NA	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	2776	ENSG00000156052
7	ENSG00000069849	NA	ATP1B3	ATPase, Na+/K+ transporting, beta 3 polypeptide	483	ENSG00000069849
8	ENSG00000164047	NA	CAMP	cathelicidin antimicrobial peptide	820	ENSG00000164047
9	ENSG00000123104	NA	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	3709	ENSG00000123104
10	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841
11	ENSG00000105409	NA	ATP1A3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	478	ENSG00000105409

Database:KEGG pathway       Name:Primary immunodeficiency       ID:05340
C=35; O=7; E=1.09; R=6.44; rawP=8.63e-05; adjP=0.0003
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000081237	NA	PTPRC	protein tyrosine phosphatase, receptor type, C	5788	ENSG00000081237
2	ENSG00000105369	NA	CD79A	CD79a molecule, immunoglobulin-associated alpha	973	ENSG00000105369
3	ENSG00000010610	NA	CD4	CD4 molecule	920	ENSG00000010610
4	ENSG00000105639	NA	JAK3	Janus kinase 3	3718	ENSG00000105639
5	ENSG00000095585	NA	BLNK	B-cell linker	29760	ENSG00000095585
6	ENSG00000196839	NA	ADA	adenosine deaminase	100	ENSG00000196839
7	ENSG00000010671	NA	BTK	Bruton agammaglobulinemia tyrosine kinase	695	ENSG00000010671

Database:KEGG pathway       Name:Phosphatidylinositol signaling system       ID:04070
C=78; O=10; E=2.42; R=4.13; rawP=0.0002; adjP=0.0006
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000133731	NA	IMPA1	inositol(myo)-1(or 4)-monophosphatase 1	3612	ENSG00000133731
2	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
3	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
4	ENSG00000168918	NA	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	3635	ENSG00000168918
5	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
6	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
7	ENSG00000123104	NA	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	3709	ENSG00000123104
8	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841
9	ENSG00000185133	NA	INPP5J	inositol polyphosphate-5-phosphatase J	27124	ENSG00000185133
10	ENSG00000163624	NA	CDS1	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1	1040	ENSG00000163624

Database:KEGG pathway       Name:Epithelial cell signaling in Helicobacter pylori infection       ID:05120
C=68; O=9; E=2.11; R=4.26; rawP=0.0002; adjP=0.0006
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
2	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
3	ENSG00000180871	NA	CXCR2	chemokine (C-X-C motif) receptor 2	3579	ENSG00000180871
4	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
5	ENSG00000158769	NA	F11R	F11 receptor	50848	ENSG00000158769
6	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
7	ENSG00000254087	NA	LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	4067	ENSG00000254087
8	ENSG00000163464	NA	CXCR1	chemokine (C-X-C motif) receptor 1	3577	ENSG00000163464
9	ENSG00000197122	NA	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	6714	ENSG00000197122

Database:KEGG pathway       Name:Protein digestion and absorption       ID:04974
C=81; O=10; E=2.52; R=3.97; rawP=0.0002; adjP=0.0006
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000155465	NA	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7	9056	ENSG00000155465
2	ENSG00000163751	NA	CPA3	carboxypeptidase A3 (mast cell)	1359	ENSG00000163751
3	ENSG00000123643	NA	SLC36A1	solute carrier family 36 (proton/amino acid symporter), member 1	206358	ENSG00000123643
4	ENSG00000104783	NA	KCNN4	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4	3783	ENSG00000104783
5	ENSG00000081052	NA	COL4A4	collagen, type IV, alpha 4	1286	ENSG00000081052
6	ENSG00000122121	NA	XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	7512	ENSG00000122121
7	ENSG00000069849	NA	ATP1B3	ATPase, Na+/K+ transporting, beta 3 polypeptide	483	ENSG00000069849
8	ENSG00000105281	NA	SLC1A5	solute carrier family 1 (neutral amino acid transporter), member 5	6510	ENSG00000105281
9	ENSG00000163359	NA	COL6A3	collagen, type VI, alpha 3	1293	ENSG00000163359
10	ENSG00000105409	NA	ATP1A3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	478	ENSG00000105409

Database:KEGG pathway       Name:Bacterial invasion of epithelial cells       ID:05100
C=70; O=9; E=2.17; R=4.14; rawP=0.0003; adjP=0.0008
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000015285	NA	WAS	Wiskott-Aldrich syndrome	7454	ENSG00000015285
2	ENSG00000112290	NA	WASF1	WAS protein family, member 1	8936	ENSG00000112290
3	ENSG00000180353	NA	HCLS1	hematopoietic cell-specific Lyn substrate 1	3059	ENSG00000180353
4	ENSG00000130429	NA	ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	10095	ENSG00000130429
5	ENSG00000162704	NA	ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	10092	ENSG00000162704
6	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
7	ENSG00000122705	NA	CLTA	clathrin, light chain A	1211	ENSG00000122705
8	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
9	ENSG00000197122	NA	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	6714	ENSG00000197122

Database:KEGG pathway       Name:Hepatitis C       ID:05160
C=134; O=13; E=4.16; R=3.12; rawP=0.0003; adjP=0.0008
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000183735	NA	TBK1	TANK-binding kinase 1	29110	ENSG00000183735
2	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
3	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
4	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
5	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
6	ENSG00000141510	NA	TP53	tumor protein p53	7157	ENSG00000141510
7	ENSG00000067182	NA	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	7132	ENSG00000067182
8	ENSG00000137275	NA	RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	8737	ENSG00000137275
9	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
10	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
11	ENSG00000124762	NA	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	1026	ENSG00000124762
12	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
13	ENSG00000137713	NA	PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	5519	ENSG00000137713

Database:KEGG pathway       Name:Melanoma       ID:05218
C=71; O=9; E=2.21; R=4.08; rawP=0.0003; adjP=0.0008
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
2	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
3	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
4	ENSG00000141510	NA	TP53	tumor protein p53	7157	ENSG00000141510
5	ENSG00000017427	NA	IGF1	insulin-like growth factor 1 (somatomedin C)	3479	ENSG00000017427
6	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
7	ENSG00000124762	NA	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	1026	ENSG00000124762
8	ENSG00000134853	NA	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	5156	ENSG00000134853
9	ENSG00000113721	NA	PDGFRB	platelet-derived growth factor receptor, beta polypeptide	5159	ENSG00000113721

Database:KEGG pathway       Name:Adherens junction       ID:04520
C=73; O=9; E=2.27; R=3.97; rawP=0.0004; adjP=0.0011
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000136153	NA	LMO7	LIM domain 7	4008	ENSG00000136153
2	ENSG00000015285	NA	WAS	Wiskott-Aldrich syndrome	7454	ENSG00000015285
3	ENSG00000112290	NA	WASF1	WAS protein family, member 1	8936	ENSG00000112290
4	ENSG00000130202	NA	PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	5819	ENSG00000130202
5	ENSG00000111679	NA	PTPN6	protein tyrosine phosphatase, non-receptor type 6	5777	ENSG00000111679
6	ENSG00000177707	NA	PVRL3	poliovirus receptor-related 3	25945	ENSG00000177707
7	ENSG00000140575	NA	IQGAP1	IQ motif containing GTPase activating protein 1	8826	ENSG00000140575
8	ENSG00000106799	NA	TGFBR1	transforming growth factor, beta receptor 1	7046	ENSG00000106799
9	ENSG00000197122	NA	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	6714	ENSG00000197122

Database:KEGG pathway       Name:Fructose and mannose metabolism       ID:00051
C=36; O=6; E=1.12; R=5.36; rawP=0.0008; adjP=0.0021
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000178802	NA	MPI	mannose phosphate isomerase	4351	ENSG00000178802
2	ENSG00000160883	NA	HK3	hexokinase 3 (white cell)	3101	ENSG00000160883
3	ENSG00000140650	NA	PMM2	phosphomannomutase 2	5373	ENSG00000140650
4	ENSG00000140263	NA	SORD	sorbitol dehydrogenase	6652	ENSG00000140263
5	ENSG00000165140	NA	FBP1	fructose-1,6-bisphosphatase 1	2203	ENSG00000165140
6	ENSG00000067057	NA	PFKP	phosphofructokinase, platelet	5214	ENSG00000067057

Database:KEGG pathway       Name:Tight junction       ID:04530
C=132; O=12; E=4.10; R=2.93; rawP=0.0009; adjP=0.0024
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000082397	NA	EPB41L3	erythrocyte membrane protein band 4.1-like 3	23136	ENSG00000082397
2	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
3	ENSG00000180353	NA	HCLS1	hematopoietic cell-specific Lyn substrate 1	3059	ENSG00000180353
4	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
5	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
6	ENSG00000163932	NA	PRKCD	protein kinase C, delta	5580	ENSG00000163932
7	ENSG00000158769	NA	F11R	F11 receptor	50848	ENSG00000158769
8	ENSG00000065135	NA	GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	2773	ENSG00000065135
9	ENSG00000114353	NA	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	2771	ENSG00000114353
10	ENSG00000197122	NA	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	6714	ENSG00000197122
11	ENSG00000137713	NA	PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	5519	ENSG00000137713
12	ENSG00000197694	NA	SPTAN1	spectrin, alpha, non-erythrocytic 1	6709	ENSG00000197694

Database:KEGG pathway       Name:Vascular smooth muscle contraction       ID:04270
C=116; O=11; E=3.60; R=3.05; rawP=0.0010; adjP=0.0026
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000087460	NA	GNAS	GNAS complex locus	2778	ENSG00000087460
2	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
3	ENSG00000163932	NA	PRKCD	protein kinase C, delta	5580	ENSG00000163932
4	ENSG00000127472	NA	PLA2G5	phospholipase A2, group V	5322	ENSG00000127472
5	ENSG00000138031	NA	ADCY3	adenylate cyclase 3	109	ENSG00000138031
6	ENSG00000156052	NA	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	2776	ENSG00000156052
7	ENSG00000123104	NA	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	3709	ENSG00000123104
8	ENSG00000163017	NA	ACTG2	actin, gamma 2, smooth muscle, enteric	72	ENSG00000163017
9	ENSG00000120063	NA	GNA13	guanine nucleotide binding protein (G protein), alpha 13	10672	ENSG00000120063
10	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841
11	ENSG00000188257	NA	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	5320	ENSG00000188257

Database:KEGG pathway       Name:ECM-receptor interaction       ID:04512
C=85; O=9; E=2.64; R=3.41; rawP=0.0013; adjP=0.0031
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000118785	NA	SPP1	secreted phosphoprotein 1	6696	ENSG00000118785
2	ENSG00000135862	NA	LAMC1	laminin, gamma 1 (formerly LAMB2)	3915	ENSG00000135862
3	ENSG00000115232	NA	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	3676	ENSG00000115232
4	ENSG00000081052	NA	COL4A4	collagen, type IV, alpha 4	1286	ENSG00000081052
5	ENSG00000164171	NA	ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	3673	ENSG00000164171
6	ENSG00000026508	NA	CD44	CD44 molecule (Indian blood group)	960	ENSG00000026508
7	ENSG00000163359	NA	COL6A3	collagen, type VI, alpha 3	1293	ENSG00000163359
8	ENSG00000005961	NA	ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	3674	ENSG00000005961
9	ENSG00000137801	NA	THBS1	thrombospondin 1	7057	ENSG00000137801

Database:KEGG pathway       Name:Amyotrophic lateral sclerosis (ALS)       ID:05014
C=53; O=7; E=1.65; R=4.25; rawP=0.0012; adjP=0.0031
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000028137	NA	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	7133	ENSG00000028137
2	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
3	ENSG00000107758	NA	PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	5532	ENSG00000107758
4	ENSG00000120868	NA	APAF1	apoptotic peptidase activating factor 1	317	ENSG00000120868
5	ENSG00000204209	NA	DAXX	death-domain associated protein	1616	ENSG00000204209
6	ENSG00000141510	NA	TP53	tumor protein p53	7157	ENSG00000141510
7	ENSG00000067182	NA	TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	7132	ENSG00000067182

Database:KEGG pathway       Name:Pantothenate and CoA biosynthesis       ID:00770
C=16; O=4; E=0.50; R=8.05; rawP=0.0013; adjP=0.0031
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000112303	NA	VNN2	vanin 2	8875	ENSG00000112303
2	ENSG00000060982	NA	BCAT1	branched chain amino-acid transaminase 1, cytosolic	586	ENSG00000060982
3	ENSG00000188641	NA	DPYD	dihydropyrimidine dehydrogenase	1806	ENSG00000188641
4	ENSG00000112299	NA	VNN1	vanin 1	8876	ENSG00000112299

Database:KEGG pathway       Name:Pentose phosphate pathway       ID:00030
C=27; O=5; E=0.84; R=5.96; rawP=0.0013; adjP=0.0031
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000160211	NA	G6PD	glucose-6-phosphate dehydrogenase	2539	ENSG00000160211
2	ENSG00000165140	NA	FBP1	fructose-1,6-bisphosphatase 1	2203	ENSG00000165140
3	ENSG00000101911	NA	PRPS2	phosphoribosyl pyrophosphate synthetase 2	5634	ENSG00000101911
4	ENSG00000067057	NA	PFKP	phosphofructokinase, platelet	5214	ENSG00000067057
5	ENSG00000142657	NA	PGD	phosphogluconate dehydrogenase	5226	ENSG00000142657

Database:KEGG pathway       Name:Insulin signaling pathway       ID:04910
C=138; O=12; E=4.29; R=2.80; rawP=0.0013; adjP=0.0031
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000181856	NA	SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	6517	ENSG00000181856
2	ENSG00000106617	NA	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	51422	ENSG00000106617
3	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
4	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
5	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
6	ENSG00000168918	NA	INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	3635	ENSG00000168918
7	ENSG00000165140	NA	FBP1	fructose-1,6-bisphosphatase 1	2203	ENSG00000165140
8	ENSG00000104812	NA	GYS1	glycogen synthase 1 (muscle)	2997	ENSG00000104812
9	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
10	ENSG00000100889	NA	PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	5106	ENSG00000100889
11	ENSG00000160883	NA	HK3	hexokinase 3 (white cell)	3101	ENSG00000160883
12	ENSG00000108946	NA	PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha	5573	ENSG00000108946

Database:KEGG pathway       Name:Progesterone-mediated oocyte maturation       ID:04914
C=86; O=9; E=2.67; R=3.37; rawP=0.0014; adjP=0.0033
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
2	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
3	ENSG00000117676	NA	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	6195	ENSG00000117676
4	ENSG00000017427	NA	IGF1	insulin-like growth factor 1 (somatomedin C)	3479	ENSG00000017427
5	ENSG00000138031	NA	ADCY3	adenylate cyclase 3	109	ENSG00000138031
6	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
7	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
8	ENSG00000065135	NA	GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	2773	ENSG00000065135
9	ENSG00000114353	NA	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	2771	ENSG00000114353

Database:KEGG pathway       Name:Long-term potentiation       ID:04720
C=70; O=8; E=2.17; R=3.68; rawP=0.0015; adjP=0.0035
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
2	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
3	ENSG00000117676	NA	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	6195	ENSG00000117676
4	ENSG00000127314	NA	RAP1B	RAP1B, member of RAS oncogene family	5908	ENSG00000127314
5	ENSG00000156052	NA	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	2776	ENSG00000156052
6	ENSG00000123104	NA	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	3709	ENSG00000123104
7	ENSG00000107758	NA	PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	5532	ENSG00000107758
8	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841

Database:KEGG pathway       Name:Bladder cancer       ID:05219
C=42; O=6; E=1.30; R=4.60; rawP=0.0018; adjP=0.0042
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000100985	NA	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	4318	ENSG00000100985
2	ENSG00000196611	NA	MMP1	matrix metallopeptidase 1 (interstitial collagenase)	4312	ENSG00000196611
3	ENSG00000124762	NA	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	1026	ENSG00000124762
4	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
5	ENSG00000141510	NA	TP53	tumor protein p53	7157	ENSG00000141510
6	ENSG00000137801	NA	THBS1	thrombospondin 1	7057	ENSG00000137801

Database:KEGG pathway       Name:Valine, leucine and isoleucine degradation       ID:00280
C=44; O=6; E=1.37; R=4.39; rawP=0.0023; adjP=0.0053
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000104951	NA	IL4I1	interleukin 4 induced 1	259307	ENSG00000104951
2	ENSG00000060982	NA	BCAT1	branched chain amino-acid transaminase 1, cytosolic	586	ENSG00000060982
3	ENSG00000117054	NA	ACADM	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	34	ENSG00000117054
4	ENSG00000183044	NA	ABAT	4-aminobutyrate aminotransferase	18	ENSG00000183044
5	ENSG00000143149	NA	ALDH9A1	aldehyde dehydrogenase 9 family, member A1	223	ENSG00000143149
6	ENSG00000138356	NA	AOX1	aldehyde oxidase 1	316	ENSG00000138356

Database:KEGG pathway       Name:Axon guidance       ID:04360
C=129; O=11; E=4.01; R=2.74; rawP=0.0024; adjP=0.0054
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000097007	NA	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	25	ENSG00000097007
2	ENSG00000163486	NA	SRGAP2	SLIT-ROBO Rho GTPase activating protein 2	23380	ENSG00000163486
3	ENSG00000167680	NA	SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	10501	ENSG00000167680
4	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
5	ENSG00000142627	NA	EPHA2	EPH receptor A2	1969	ENSG00000142627
6	ENSG00000143590	NA	EFNA3	ephrin-A3	1944	ENSG00000143590 ENSG00000251246
7	ENSG00000184349	NA	EFNA5	ephrin-A5	1946	ENSG00000184349
8	ENSG00000107758	NA	PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	5532	ENSG00000107758
9	ENSG00000065135	NA	GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	2773	ENSG00000065135
10	ENSG00000114353	NA	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	2771	ENSG00000114353
11	ENSG00000182511	NA	FES	feline sarcoma oncogene	2242	ENSG00000182511

Database:KEGG pathway       Name:Glycerophospholipid metabolism       ID:00564
C=80; O=8; E=2.49; R=3.22; rawP=0.0034; adjP=0.0076
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000087253	NA	LPCAT2	lysophosphatidylcholine acyltransferase 2	54947	ENSG00000087253
2	ENSG00000127472	NA	PLA2G5	phospholipase A2, group V	5322	ENSG00000127472
3	ENSG00000139163	NA	ETNK1	ethanolamine kinase 1	55500	ENSG00000139163
4	ENSG00000153395	NA	LPCAT1	lysophosphatidylcholine acyltransferase 1	79888	ENSG00000153395
5	ENSG00000163803	NA	PLB1	phospholipase B1	151056	ENSG00000163803
6	ENSG00000241878	NA	PISD	phosphatidylserine decarboxylase	23761	ENSG00000241878
7	ENSG00000188257	NA	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	5320	ENSG00000188257
8	ENSG00000163624	NA	CDS1	CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1	1040	ENSG00000163624

Database:KEGG pathway       Name:N-Glycan biosynthesis       ID:00510
C=49; O=6; E=1.52; R=3.94; rawP=0.0040; adjP=0.0087
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000120697	NA	ALG5	asparagine-linked glycosylation 5, dolichyl-phosphate beta-glucosyltransferase homolog (S. cerevisiae)	29880	ENSG00000120697
2	ENSG00000119523	NA	ALG2	asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae)	85365	ENSG00000119523
3	ENSG00000131446	NA	MGAT1	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	4245	ENSG00000131446
4	ENSG00000163933	NA	RFT1	RFT1 homolog (S. cerevisiae)	91869	ENSG00000163933
5	ENSG00000111885	NA	MAN1A1	mannosidase, alpha, class 1A, member 1	4121	ENSG00000111885
6	ENSG00000112893	NA	MAN2A1	mannosidase, alpha, class 2A, member 1	4124	ENSG00000112893

Database:KEGG pathway       Name:Glycolysis / Gluconeogenesis       ID:00010
C=65; O=7; E=2.02; R=3.47; rawP=0.0040; adjP=0.0087
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000100889	NA	PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	5106	ENSG00000100889
2	ENSG00000160883	NA	HK3	hexokinase 3 (white cell)	3101	ENSG00000160883
3	ENSG00000196616	NA	ADH1B	alcohol dehydrogenase 1B (class I), beta polypeptide	125	ENSG00000196616
4	ENSG00000165140	NA	FBP1	fructose-1,6-bisphosphatase 1	2203	ENSG00000165140
5	ENSG00000067057	NA	PFKP	phosphofructokinase, platelet	5214	ENSG00000067057
6	ENSG00000184254	NA	ALDH1A3	aldehyde dehydrogenase 1 family, member A3	220	ENSG00000184254
7	ENSG00000143149	NA	ALDH9A1	aldehyde dehydrogenase 9 family, member A1	223	ENSG00000143149

Database:KEGG pathway       Name:beta-Alanine metabolism       ID:00410
C=22; O=4; E=0.68; R=5.85; rawP=0.0043; adjP=0.0090
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000117054	NA	ACADM	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	34	ENSG00000117054
2	ENSG00000183044	NA	ABAT	4-aminobutyrate aminotransferase	18	ENSG00000183044
3	ENSG00000188641	NA	DPYD	dihydropyrimidine dehydrogenase	1806	ENSG00000188641
4	ENSG00000143149	NA	ALDH9A1	aldehyde dehydrogenase 9 family, member A1	223	ENSG00000143149

Database:KEGG pathway       Name:Melanogenesis       ID:04916
C=101; O=9; E=3.14; R=2.87; rawP=0.0043; adjP=0.0090
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000087460	NA	GNAS	GNAS complex locus	2778	ENSG00000087460
2	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
3	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
4	ENSG00000177283	NA	FZD8	frizzled family receptor 8	8325	ENSG00000177283
5	ENSG00000138031	NA	ADCY3	adenylate cyclase 3	109	ENSG00000138031
6	ENSG00000156052	NA	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	2776	ENSG00000156052
7	ENSG00000065135	NA	GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	2773	ENSG00000065135
8	ENSG00000114353	NA	GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	2771	ENSG00000114353
9	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841

Database:KEGG pathway       Name:Prion diseases       ID:05020
C=35; O=5; E=1.09; R=4.60; rawP=0.0043; adjP=0.0090
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000173369	NA	C1QB	complement component 1, q subcomponent, B chain	713	ENSG00000173369
2	ENSG00000173372	NA	C1QA	complement component 1, q subcomponent, A chain	712	ENSG00000173372
3	ENSG00000135862	NA	LAMC1	laminin, gamma 1 (formerly LAMB2)	3915	ENSG00000135862
4	ENSG00000112936	NA	C7	complement component 7	730	ENSG00000112936
5	ENSG00000159189	NA	C1QC	complement component 1, q subcomponent, C chain	714	ENSG00000159189

Database:KEGG pathway       Name:Proximal tubule bicarbonate reclamation       ID:04964
C=23; O=4; E=0.71; R=5.60; rawP=0.0051; adjP=0.0106
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000069849	NA	ATP1B3	ATPase, Na+/K+ transporting, beta 3 polypeptide	483	ENSG00000069849
2	ENSG00000100889	NA	PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	5106	ENSG00000100889
3	ENSG00000105409	NA	ATP1A3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	478	ENSG00000105409
4	ENSG00000183048	NA	SLC25A10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	1468	ENSG00000262660 ENSG00000183048

Database:KEGG pathway       Name:mTOR signaling pathway       ID:04150
C=52; O=6; E=1.62; R=3.71; rawP=0.0054; adjP=0.0111
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
2	ENSG00000100644	NA	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	3091	ENSG00000100644
3	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
4	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
5	ENSG00000117676	NA	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	6195	ENSG00000117676
6	ENSG00000017427	NA	IGF1	insulin-like growth factor 1 (somatomedin C)	3479	ENSG00000017427

Database:KEGG pathway       Name:Pancreatic cancer       ID:05212
C=70; O=7; E=2.17; R=3.22; rawP=0.0060; adjP=0.0119
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000106799	NA	TGFBR1	transforming growth factor, beta receptor 1	7046	ENSG00000106799
2	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
3	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
4	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
5	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
6	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
7	ENSG00000141510	NA	TP53	tumor protein p53	7157	ENSG00000141510

Database:KEGG pathway       Name:Nicotinate and nicotinamide metabolism       ID:00760
C=24; O=4; E=0.75; R=5.36; rawP=0.0060; adjP=0.0119
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000106733	NA	NMRK1	nicotinamide riboside kinase 1	54981	ENSG00000106733
2	ENSG00000166741	NA	NNMT	nicotinamide N-methyltransferase	4837	ENSG00000166741
3	ENSG00000112874	NA	NUDT12	nudix (nucleoside diphosphate linked moiety X)-type motif 12	83594	ENSG00000112874
4	ENSG00000138356	NA	AOX1	aldehyde oxidase 1	316	ENSG00000138356

Database:KEGG pathway       Name:Renal cell carcinoma       ID:05211
C=70; O=7; E=2.17; R=3.22; rawP=0.0060; adjP=0.0119
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
2	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
3	ENSG00000134954	NA	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	2113	ENSG00000134954
4	ENSG00000100644	NA	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	3091	ENSG00000100644
5	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
6	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
7	ENSG00000127314	NA	RAP1B	RAP1B, member of RAS oncogene family	5908	ENSG00000127314

Database:KEGG pathway       Name:RIG-I-like receptor signaling pathway       ID:04622
C=71; O=7; E=2.21; R=3.17; rawP=0.0065; adjP=0.0128
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000137275	NA	RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	8737	ENSG00000137275
2	ENSG00000156711	NA	MAPK13	mitogen-activated protein kinase 13	5603	ENSG00000156711
3	ENSG00000183735	NA	TBK1	TANK-binding kinase 1	29110	ENSG00000183735
4	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
5	ENSG00000121060	NA	TRIM25	tripartite motif containing 25	7706	ENSG00000121060
6	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320
7	ENSG00000168040	NA	FADD	Fas (TNFRSF6)-associated via death domain	8772	ENSG00000168040

Database:KEGG pathway       Name:Dilated cardiomyopathy       ID:05414
C=90; O=8; E=2.80; R=2.86; rawP=0.0070; adjP=0.0136
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000087460	NA	GNAS	GNAS complex locus	2778	ENSG00000087460
2	ENSG00000115232	NA	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	3676	ENSG00000115232
3	ENSG00000164171	NA	ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	3673	ENSG00000164171
4	ENSG00000167460	NA	TPM4	tropomyosin 4	7171	ENSG00000167460
5	ENSG00000017427	NA	IGF1	insulin-like growth factor 1 (somatomedin C)	3479	ENSG00000017427
6	ENSG00000138031	NA	ADCY3	adenylate cyclase 3	109	ENSG00000138031
7	ENSG00000160789	NA	LMNA	lamin A/C	4000	ENSG00000160789
8	ENSG00000005961	NA	ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	3674	ENSG00000005961

Database:KEGG pathway       Name:Sphingolipid metabolism       ID:00600
C=40; O=5; E=1.24; R=4.02; rawP=0.0077; adjP=0.0147
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000170266	NA	GLB1	galactosidase, beta 1	2720	ENSG00000170266
2	ENSG00000090054	NA	SPTLC1	serine palmitoyltransferase, long chain base subunit 1	10558	ENSG00000090054
3	ENSG00000148154	NA	UGCG	UDP-glucose ceramide glucosyltransferase	7357	ENSG00000148154
4	ENSG00000100596	NA	SPTLC2	serine palmitoyltransferase, long chain base subunit 2	9517	ENSG00000100596
5	ENSG00000126821	NA	SGPP1	sphingosine-1-phosphate phosphatase 1	81537	ENSG00000126821

Database:KEGG pathway       Name:Cytosolic DNA-sensing pathway       ID:04623
C=56; O=6; E=1.74; R=3.45; rawP=0.0077; adjP=0.0147
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000137275	NA	RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	8737	ENSG00000137275
2	ENSG00000150782	NA	IL18	interleukin 18 (interferon-gamma-inducing factor)	3606	ENSG00000150782
3	ENSG00000183735	NA	TBK1	TANK-binding kinase 1	29110	ENSG00000183735
4	ENSG00000173039	NA	RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	5970	ENSG00000173039
5	ENSG00000103490	NA	PYCARD	PYD and CARD domain containing	29108	ENSG00000103490
6	ENSG00000109320	NA	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	4790	ENSG00000109320

Database:KEGG pathway       Name:Inositol phosphate metabolism       ID:00562
C=57; O=6; E=1.77; R=3.39; rawP=0.0084; adjP=0.0158
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000133731	NA	IMPA1	inositol(myo)-1(or 4)-monophosphatase 1	3612	ENSG00000133731
2	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
3	ENSG00000185133	NA	INPP5J	inositol polyphosphate-5-phosphatase J	27124	ENSG00000185133
4	ENSG00000137841	NA	PLCB2	phospholipase C, beta 2	5330	ENSG00000137841
5	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
6	ENSG00000151151	NA	IPMK	inositol polyphosphate multikinase	253430	ENSG00000151151

Database:KEGG pathway       Name:Tryptophan metabolism       ID:00380
C=42; O=5; E=1.30; R=3.83; rawP=0.0094; adjP=0.0176
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000104951	NA	IL4I1	interleukin 4 induced 1	259307	ENSG00000104951
2	ENSG00000116874	NA	WARS2	tryptophanyl tRNA synthetase 2, mitochondrial	10352	ENSG00000116874
3	ENSG00000115919	NA	KYNU	kynureninase	8942	ENSG00000115919
4	ENSG00000143149	NA	ALDH9A1	aldehyde dehydrogenase 9 family, member A1	223	ENSG00000143149
5	ENSG00000138356	NA	AOX1	aldehyde oxidase 1	316	ENSG00000138356

Database:KEGG pathway       Name:Glycosphingolipid biosynthesis - ganglio series       ID:00604
C=15; O=3; E=0.47; R=6.44; rawP=0.0103; adjP=0.0190
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000170266	NA	GLB1	galactosidase, beta 1	2720	ENSG00000170266
2	ENSG00000101638	NA	ST8SIA5	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5	29906	ENSG00000101638
3	ENSG00000115525	NA	ST3GAL5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	8869	ENSG00000115525

Database:KEGG pathway       Name:Vasopressin-regulated water reabsorption       ID:04962
C=44; O=5; E=1.37; R=3.66; rawP=0.0114; adjP=0.0209
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000087460	NA	GNAS	GNAS complex locus	2778	ENSG00000087460
2	ENSG00000138031	NA	ADCY3	adenylate cyclase 3	109	ENSG00000138031
3	ENSG00000144635	NA	DYNC1LI1	dynein, cytoplasmic 1, light intermediate chain 1	51143	ENSG00000144635
4	ENSG00000108774	NA	RAB5C	RAB5C, member RAS oncogene family	5878	ENSG00000108774
5	ENSG00000141522	NA	ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	396	ENSG00000141522

Database:KEGG pathway       Name:Primary bile acid biosynthesis       ID:00120
C=16; O=3; E=0.50; R=6.03; rawP=0.0124; adjP=0.0225
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000242110	NA	AMACR	alpha-methylacyl-CoA racemase	23600	ENSG00000242110
2	ENSG00000172817	NA	CYP7B1	cytochrome P450, family 7, subfamily B, polypeptide 1	9420	ENSG00000172817
3	ENSG00000036530	NA	CYP46A1	cytochrome P450, family 46, subfamily A, polypeptide 1	10858	ENSG00000036530

Database:KEGG pathway       Name:Mucin type O-Glycan biosynthesis       ID:00512
C=30; O=4; E=0.93; R=4.29; rawP=0.0134; adjP=0.0240
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000115339	NA	GALNT3	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)	2591	ENSG00000115339
2	ENSG00000185274	NA	WBSCR17	Williams-Beuren syndrome chromosome region 17	64409	ENSG00000185274
3	ENSG00000139629	NA	GALNT6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)	11226	ENSG00000139629
4	ENSG00000187210	NA	GCNT1	glucosaminyl (N-acetyl) transferase 1, core 2	2650	ENSG00000187210

Database:KEGG pathway       Name:Hypertrophic cardiomyopathy (HCM)       ID:05410
C=83; O=7; E=2.58; R=2.71; rawP=0.0148; adjP=0.0263
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000106617	NA	PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	51422	ENSG00000106617
2	ENSG00000115232	NA	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	3676	ENSG00000115232
3	ENSG00000005961	NA	ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	3674	ENSG00000005961
4	ENSG00000164171	NA	ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	3673	ENSG00000164171
5	ENSG00000160789	NA	LMNA	lamin A/C	4000	ENSG00000160789
6	ENSG00000167460	NA	TPM4	tropomyosin 4	7171	ENSG00000167460
7	ENSG00000017427	NA	IGF1	insulin-like growth factor 1 (somatomedin C)	3479	ENSG00000017427

Database:KEGG pathway       Name:Type II diabetes mellitus       ID:04930
C=48; O=5; E=1.49; R=3.35; rawP=0.0163; adjP=0.0287
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000181856	NA	SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	6517	ENSG00000181856
2	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
3	ENSG00000160883	NA	HK3	hexokinase 3 (white cell)	3101	ENSG00000160883
4	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
5	ENSG00000163932	NA	PRKCD	protein kinase C, delta	5580	ENSG00000163932

Database:KEGG pathway       Name:Glutathione metabolism       ID:00480
C=50; O=5; E=1.55; R=3.22; rawP=0.0192; adjP=0.0335
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000131067	NA	GGT7	gamma-glutamyltransferase 7	2686	ENSG00000131067
2	ENSG00000001084	NA	GCLC	glutamate-cysteine ligase, catalytic subunit	2729	ENSG00000001084
3	ENSG00000160211	NA	G6PD	glucose-6-phosphate dehydrogenase	2539	ENSG00000160211
4	ENSG00000166825	NA	ANPEP	alanyl (membrane) aminopeptidase	290	ENSG00000166825
5	ENSG00000142657	NA	PGD	phosphogluconate dehydrogenase	5226	ENSG00000142657

Database:KEGG pathway       Name:RNA transport       ID:03013
C=151; O=10; E=4.69; R=2.13; rawP=0.0199; adjP=0.0344
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000136243	NA	NUPL2	nucleoporin like 2	11097	ENSG00000136243
2	ENSG00000178718	NA	RPP25	ribonuclease P/MRP 25kDa subunit	54913	ENSG00000178718
3	ENSG00000093000	NA	NUP50	nucleoporin 50kDa	10762	ENSG00000093000
4	ENSG00000175390	NA	EIF3F	eukaryotic translation initiation factor 3, subunit F	8665	ENSG00000175390
5	ENSG00000150459	NA	SAP18	Sin3A-associated protein, 18kDa	10284	ENSG00000150459
6	ENSG00000120253	NA	NUP43	nucleoporin 43kDa	348995	ENSG00000120253
7	ENSG00000114784	NA	EIF1B	eukaryotic translation initiation factor 1B	10289	ENSG00000114784
8	ENSG00000070756	NA	PABPC1	poly(A) binding protein, cytoplasmic 1	26986	ENSG00000070756
9	ENSG00000085415	NA	SEH1L	SEH1-like (S. cerevisiae)	81929	ENSG00000085415
10	ENSG00000101888	NA	NXT2	nuclear transport factor 2-like export factor 2	55916	ENSG00000101888

Database:KEGG pathway       Name:PPAR signaling pathway       ID:03320
C=70; O=6; E=2.17; R=2.76; rawP=0.0216; adjP=0.0369
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000196611	NA	MMP1	matrix metallopeptidase 1 (interstitial collagenase)	4312	ENSG00000196611
2	ENSG00000197142	NA	ACSL5	acyl-CoA synthetase long-chain family member 5	51703	ENSG00000197142
3	ENSG00000112033	NA	PPARD	peroxisome proliferator-activated receptor delta	5467	ENSG00000112033
4	ENSG00000117054	NA	ACADM	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	34	ENSG00000117054
5	ENSG00000100889	NA	PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	5106	ENSG00000100889
6	ENSG00000100979	NA	PLTP	phospholipid transfer protein	5360	ENSG00000100979

Database:KEGG pathway       Name:Endometrial cancer       ID:05213
C=52; O=5; E=1.62; R=3.09; rawP=0.0224; adjP=0.0380
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000213281	NA	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	4893	ENSG00000213281
2	ENSG00000171608	NA	PIK3CD	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta	5293	ENSG00000171608
3	ENSG00000141506	NA	PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	23533	ENSG00000141506
4	ENSG00000117020	NA	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	10000	ENSG00000117020
5	ENSG00000141510	NA	TP53	tumor protein p53	7157	ENSG00000141510

Database:KEGG pathway       Name:Bile secretion       ID:04976
C=71; O=6; E=2.21; R=2.72; rawP=0.0230; adjP=0.0383
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000087460	NA	GNAS	GNAS complex locus	2778	ENSG00000087460
2	ENSG00000138031	NA	ADCY3	adenylate cyclase 3	109	ENSG00000138031
3	ENSG00000108846	NA	ABCC3	ATP-binding cassette, sub-family C (CFTR/MRP), member 3	8714	ENSG00000108846
4	ENSG00000069849	NA	ATP1B3	ATPase, Na+/K+ transporting, beta 3 polypeptide	483	ENSG00000069849
5	ENSG00000103569	NA	AQP9	aquaporin 9	366	ENSG00000103569
6	ENSG00000105409	NA	ATP1A3	ATPase, Na+/K+ transporting, alpha 3 polypeptide	478	ENSG00000105409

Database:KEGG pathway       Name:alpha-Linolenic acid metabolism       ID:00592
C=20; O=3; E=0.62; R=4.83; rawP=0.0230; adjP=0.0383
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000163803	NA	PLB1	phospholipase B1	151056	ENSG00000163803
2	ENSG00000127472	NA	PLA2G5	phospholipase A2, group V	5322	ENSG00000127472
3	ENSG00000188257	NA	PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	5320	ENSG00000188257

Database:KEGG pathway       Name:Oocyte meiosis       ID:04114
C=112; O=8; E=3.48; R=2.30; rawP=0.0237; adjP=0.0391
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000117676	NA	RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	6195	ENSG00000117676
2	ENSG00000017427	NA	IGF1	insulin-like growth factor 1 (somatomedin C)	3479	ENSG00000017427
3	ENSG00000138031	NA	ADCY3	adenylate cyclase 3	109	ENSG00000138031
4	ENSG00000164924	NA	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	7534	ENSG00000164924
5	ENSG00000123104	NA	ITPR2	inositol 1,4,5-trisphosphate receptor, type 2	3709	ENSG00000123104
6	ENSG00000107758	NA	PPP3CB	protein phosphatase 3, catalytic subunit, beta isozyme	5532	ENSG00000107758
7	ENSG00000137713	NA	PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	5519	ENSG00000137713
8	ENSG00000112029	NA	FBXO5	F-box protein 5	26271	ENSG00000112029

Database:KEGG pathway       Name:Vibrio cholerae infection       ID:05110
C=54; O=5; E=1.68; R=2.98; rawP=0.0259; adjP=0.0419
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000087460	NA	GNAS	GNAS complex locus	2778	ENSG00000087460
2	ENSG00000138031	NA	ADCY3	adenylate cyclase 3	109	ENSG00000138031
3	ENSG00000166501	NA	PRKCB	protein kinase C, beta	5579	ENSG00000166501
4	ENSG00000197943	NA	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	5336	ENSG00000197943
5	ENSG00000065665	NA	SEC61A2	Sec61 alpha 2 subunit (S. cerevisiae)	55176	ENSG00000065665

Database:KEGG pathway       Name:Starch and sucrose metabolism       ID:00500
C=54; O=5; E=1.68; R=2.98; rawP=0.0259; adjP=0.0419
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000104812	NA	GYS1	glycogen synthase 1 (muscle)	2997	ENSG00000104812
2	ENSG00000165434	NA	PGM2L1	phosphoglucomutase 2-like 1	283209	ENSG00000165434
3	ENSG00000118094	NA	TREH	trehalase (brush-border membrane glycoprotein)	11181	ENSG00000118094
4	ENSG00000160883	NA	HK3	hexokinase 3 (white cell)	3101	ENSG00000160883
5	ENSG00000109814	NA	UGDH	UDP-glucose 6-dehydrogenase	7358	ENSG00000109814

Database:KEGG pathway       Name:Allograft rejection       ID:05330
C=37; O=4; E=1.15; R=3.48; rawP=0.0272; adjP=0.0437
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000136634	NA	IL10	interleukin 10	3586	ENSG00000136634
2	ENSG00000114013	NA	CD86	CD86 molecule	942	ENSG00000114013
3	ENSG00000178562	NA	CD28	CD28 molecule	940	ENSG00000178562
4	ENSG00000026103	NA	FAS	Fas (TNF receptor superfamily, member 6)	355	ENSG00000026103

Database:KEGG pathway       Name:Glycosaminoglycan biosynthesis - chondroitin sulfate       ID:00532
C=22; O=3; E=0.68; R=4.39; rawP=0.0297; adjP=0.0473
Index	UserID	Value	Gene Symbol	Gene Name	EntrezGene	Ensembl
1	ENSG00000131873	NA	CHSY1	chondroitin sulfate synthase 1	22856	ENSG00000131873
2	ENSG00000171310	NA	CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	50515	ENSG00000171310
3	ENSG00000182022	NA	CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15	51363	ENSG00000182022

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WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).